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General Information
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Product
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CXCR1 Antibody
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Description
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Affinity Purified IL-8 receptor type A Antibody C-epitope
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Verified Applications
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ELISA, ICC/IF, IHC-P, IP
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Host
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Rabbit
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Species Cross Reactivity
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Human
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Immunogen
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Synthetic peptide, corresponding to a region within C terminal amino acids 272-350 of Human CXCR1.
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Accession #
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GenBank: BAA92293.1
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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5-.75 µg/µl in antibody stabilization buffer
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Form
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Affinity Purified
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Clonality
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Polyclonal
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Determinant
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C-epitope
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Storage
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-20⁰C for long term storage
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Application Protocol
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DB
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1:10,000
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ELISA
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1:10,000
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| Immunohistochemistry |
1:100-1:1000 |
| Immunofluorescence |
1:100-1:1000 |
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Immunoprecipitation
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1:250
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Western Blot
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1:500. Predicted molecular weight: 40 kDa.
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Protein
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Uniprot #
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P25024
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Overview
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Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL-8 with a high affinity and to MGSA (GRO) with a low affinity.
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Molecular Function
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Chemotaxis
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Subcellular Location
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Cell membrane; Multi-pass membrane protein
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Structure
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Belongs to the G-protein coupled receptor 1 family
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Alternative Nomenclature
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C C antibody
C C CKR 1 antibody
C-X-C chemokine receptor type 1 antibody
CCCKR1 antibody
CD 181 antibody
CD128 antibody
CKR 1 antibody
CMKAR1 antibody
CXC-R1 antibody
High affinity interleukin-8 receptor A antibody
IL 8 receptor type 1 antibody
IL 8R A antibody
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CXCR1 Antibody FITC
CXCR1 Antibody BIOTIN
CXCR1 Blocking Peptide
CXCR1 Positive Control
