Cytokeratin 20 Antibody

General Information

Product

Cytokeratin 20 Antibody

Description

Affinity Purified keratin, type I cytoskeletal 20 Antibody N-epitope

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey, Mouse

Immunogen

Synthetic peptide taken within amino acid region 300-350 human keratin, type I cytoskeletal 20 protein.

Accession #

NCBI:  NP_061883.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

N-epitope

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:150

Western Blot

1:500

Protein

Uniprot #

P35900

Overview

Plays a role in maintaining keratin filament organization in intestinal epithelia.  When phosphorlyated it is involved in the secretion of mucin in the small intestine.

Molecular Function

Structural constituent of cytoskeleton; Apoptosis

Subcellular Location

Cytoplasm

Expression

Mainly expressed in the itenstinal epithelium, expressed in luminal cells of colonic mucosa.  Also expressed in Merkel cells of keratinzed oral mucosa.

Structure

Heterotetramer of two type I and two type II keratins, associates with KRT8.

Alternative Nomenclature

CD20 antibody

CK20 antibody

Cytokeratin20 antibody

K20 antibody

Keratin 20 antibody

keratin 21, rat, homolog of antibody

Keratin antibody

Keratin type I cytoskeletal 20 antibody

KRT20 antibody

KRT21 antibody

Protein IT antibody

type I cytoskeletal 20 antibody