DAPK2 Antibody BIOTIN

Product no.: DAPK2-BIOTIN
$375.00


General Information

 

 

Product

 

DAPK2 Antibody BIOTIN

Description

BIOTIN-Conjugated Death-associated protein kinase 2 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide take within amino acid region 300-350 on mouse Death-associated protein kinase 2 protein.


Physical Properties

 

 

Quantity

 

100 µg

Volume

200 µl

Concentration

0.5-1.5 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

BIOTIN-Conjugated

Purification Method

Immobilized antigen affinity chromatography

Clonality

Polyclonal

Storage

-20C for long term storage


Application Protocol

 

ELISA

 

1:50,000

Immunohistochemistry 1:50-1:150

Immunoprecipitation

1:200

Western Blot

1:2,500-1:5,000


Protein

 

Uniprot #

 

Q8VDF3

Overview

Calcium/calmodulin-dependent serine/threonine kinase involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and autophagy. Capable of regulating both type I apoptotic and type II autophagic cell death signals.

Molecular Function

ATP binding

calmodulin binding

identical protein binding

protein serine/threonine kinase activity

Subcellular Location

Cytoplasm

autophagosome lumen

Expression

Expressed in peritubular interstitial cells of the renal cortex (PubMed:24906443). Isoform 1 is found in the adult brain while isoform 2 is expressed in brains of embryos and young mice (at protein level) (PubMed:21408167).

Structure

The autoinhibitory domain sterically blocks the substrate peptide-binding site by making both hydrophobic and electrostatic contacts with the kinase core.

Alternative Nomenclature

DAK2 antibody

DAP kinase 2 antibody

DAP kinase related protein 1 antibody

DAP kinase related protein 1 beta isoform antibody

DAP-kinase-related protein 1 antibody

DAPK2 antibody

Death associated protein kinase 2 antibody

DRP 1 antibody

   

Protein information supplied by UniProt.

 

Accessories

Product Note Status Price
DAPK2 Antibody DAPK2 Antibody
DAPK2-201AP $285.00 *
DAPK2 Positive Control DAPK2 Positive Control
PC-DAPK2 $200.00 *
DAPK2 Blocking Peptide DAPK2 Blocking Peptide
P-DAPK2 $155.00 *
DAPK2 Antibody FITC DAPK2 Antibody FITC
DAPK2-FITC $375.00 *
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