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General Information
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Product
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EDG8 Peptide
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Description
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Antigenic Blocking Peptide Sphingosine 1-phosphate receptor 5
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Verified Applications
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Immunodepletion, Immunocompetition
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Peptide Description
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Synthetic peptide taken within amino acid region 380-400 of rat S1P5R/EDG8 protein.
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Physical Properties
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Quantity
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250 µg
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Volume
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100 µl
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Form
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Antigenic Blocking Peptide
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Storage
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-20⁰C for long term storage
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Application Protocol
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Competition/Depletion assay
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Refer to competition assay protocol
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Protein
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Uniprot #
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Q9JKM5
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Overview
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Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. Is coupled to both the G(i/O)alpha and G(12) subclass of heteromeric G-proteins.
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Molecular Function
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G-protein coupled receptor, Receptor, Transducer
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Subcellular Location
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Cell membrane; Multi-pass membrane protein
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Expression
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Found almost exclusively in brain and skin. Ubiquitously detected in different brain regions with very prominent expression in lower brain regions such as the midbrain, pons, medulla, and spinal cord. Expressed predominantly within white matter tracts of
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Alternative Nomenclature
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EDG 8 antibody
Endothelial differentiation G protein coupled receptor 8 antibody
Endothelial differentiation sphingolipid G protein coupled receptor 8 antibody
S1P receptor 5 antibody
S1P receptor Edg 8 antibody
Sphingosine 1 Phosphate Receptor 5 antibody
Sphingosine 1-phosphate receptor Edg-8 antibody
SPPR2 antibody
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EDG8 Antibody
EDG8 Antibody FITC
EDG8 Antibody BIOTIN
EDG8 Positive Control
