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General Information
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Product
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FOLR1 Peptide
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Description
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Antigenic Blocking Peptide Folate receptor Alpha
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Verified Applications
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Immunodepletion, Immunocompetition
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Peptide Description
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Synthetic peptide taken within amino acid region 200-250 on mouse Folate receptor alpha protein.
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Physical Properties
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Quantity
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250 µg
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Volume
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100 µl
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Form
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Antigenic Blocking Peptide
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Storage
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-20⁰C for long term storage
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Application Protocol
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Competition/Depletion assay
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Refer to competition assay protocol
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Protein
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Uniprot #
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P35846
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Overview
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Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release. Required for normal embryonic development and normal cell proliferation. Required for renal folate reabsorption.
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Molecular Function
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Receptor
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Subcellular Location
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Cell membrane, Cytoplasmic vesicle, Endosome, Membrane, Secreted
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Expression
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Detected in kidney proximal tubules.
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Structure
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Belongs to the folate receptor family.
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Alternative Nomenclature
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adult antibody
Adult folate binding protein antibody
FBP antibody
Folate Receptor 1 Adult antibody
Folate receptor 1 antibody
Folate receptor alpha antibody
Folate receptor antibody
FOLR antibody
FOLR1 antibody
FR alpha antibody
KB cells FBP antibody
MOV18 antibody
Ovarian cancer associated antigen antibody
Ovarian tumor associated antigen MOv18 antibody
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FOLR1 Antibody
FOLR1 Antibody BIOTIN
FOLR1 Antibody FITC
FOLR1 Positive Control
