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General Information
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Product
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FPR1 Peptide
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Description
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Antigenic Blocking Peptide N-formyl peptide receptor
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Verified Applications
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Immunodepletion, Immunocompetition
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Peptide Description
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Synthetic peptide taken within amino acid region 150-200 on N-formyl peptide receptor.
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Accession #
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GenBank: AAA16863.1
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Physical Properties
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Quantity
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250 µg
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Volume
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100 µl
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Form
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Antigenic Blocking Peptide
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Storage
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-20⁰C for long term storage
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Application Protocol
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Competition/Depletion assay
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Refer to competition assay protocol
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Protein
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Uniprot #
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P21462
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Overview
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High affinity receptor for N-formyl-methionyl peptides (fMLP), which are powerful neutrophil chemotactic factors (PubMed:2161213, PubMed:2176894, PubMed:10514456, PubMed:15153520). Binding of fMLP to the receptor stimulates intracellular calcium mobilization and superoxide anion release (PubMed:2161213, PubMed:1712023, PubMed:15153520). This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system (PubMed:1712023, PubMed:10514456).
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Molecular Function
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N-formyl peptide receptor activity; Receptor activity
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Subcellular Location
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Cell membrane; Multi-pass membrane
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Structure
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Belongs to the G-protein coupled receptor 1 family.
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Alternative Nomenclature
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fMet Leu Phe receptor antibody
FMLP antibody
FMLPR antibody
Formyl peptide receptor 1 antibody
FPR 1 antibody
FPR receptor antibody
N formyl peptide chemoattractant receptor antibody
N formyl peptide receptor antibody
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FPR1 Antibody
FPR1 Antibody BIOTIN
FPR1 Antibody FITC
FPR1 Positive Control
