Granzyme B Blocking Peptide

General Information

Product

Granzyme B Peptide

Description

Antigenic Blocking Peptide Granzyme B Antibody C-epitope

Verified Applications

Immunodepletion, Immunocompetition

mmunogen

Synthetic peptide taken within amino acid region 50-100 on human endogenous Granzyme B protein.

Accession #

GenBank:  AAR23323.1

Physical Properties

Quantity

250 µg

Volume

100 µl

Form

Antigenic Blocking Peptide

Determinant

C-epitope

Storage

-20⁰C for long term storage

Application Protocol

Competition/Depletion assay

Refer to competition assay protocol

Protein

Uniprot #

P10144

Overview

This enzyme is necessary for target cell lysis in cell-mediated immune responses;Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.

Molecular Function

Hydrolase, Protease, Serine protease

Subcellular Location

intracellular membrane-bounded organelle;nucleus;cytoplasm

Expression

leukocyte;adipose tissue;appendix;bladder;bone marrow;colon;duodenum;endometrium

Alternative Nomenclature

C11 antibody

Cathepsin G like 1 antibody

CCPI antibody

CGL 1 antibody

CSP B antibody

CTLA 1 antibody

CTSGL 1 antibody

Cytotoxic serine protease B antibody

Cytotoxic T Lymphocyte Associated Serine Esterase 1 antibody

Cytotoxic T lymphocyte proteinase 2 antibody

Fragmentin 2 antibody

Granzyme B (granzyme 2, cytotoxic T lymphocyte associated serine esterase 1) antibody

Granzyme-2 antibody

GRB antibody

GZMB antibody

HLP antibody

Human lymphocyte protein antibody

Lymphocyte protease antibody

Protease Serine B antibody

SECT antibody

T-cell serine protease 1-3E antibody