General Information
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Product
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IL18RAP Peptide
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Description
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Antigenic Blocking Peptide Interleukin-18 receptor accessory protein Antibody
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Verified Applications
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Immunodepletion, Immunocompetition
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Peptide Description
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Synthetic peptide taken within amino acid region 500-550 on human Interleukin-18 receptor accessory protein.
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Physical Properties
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Quantity
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250 µg
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Volume
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100 µl
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Form
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Antigenic Blocking Peptide
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Storage
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-20⁰C for long term storage
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Application Protocol
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Competition/Depletion assay
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Refer to competition assay protocol
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Protein
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Uniprot #
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O95256
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Overview
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Within the IL18 receptor complex, does not mediate IL18-binding, but involved in IL18-dependent signal transduction, leading to NF-kappa-B and JNK activation.
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Molecular Function
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Receptor activity
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Subcellular Location
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Membrane, Single-pass type I membrane protein
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Expression
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Strongly expressed in peripheral blood leukocytes, spleen, lung, and, to a lesser extent, in colon, but not in any other tissue tested. Strongly expressed in T-cells polarized with IL-12. Specifically coexpressed with IL18R1 in Th1 cells.
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Structure
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Belongs to the interleukin-1 receptor family.
Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
Contains 1 TIR domain.
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Alternative Nomenclature
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IL18RAP antibody
Accessory protein like antibody
AcPL antibody
CD218 antigen-like family member B antibody
CDw218b antibody
IL-18R-beta antibody
IL-18RAcP antibody
IL-18Rbeta antibody
IL-1R accessory protein-like antibody
IL-1R7 antibody
IL-1RAcPL antibody
IL18RAP antibody
IL18Rbeta antibody
Interleukin 18 receptor accessory protein antibody
Interleukin-1 receptor 7 antibody
Interleukin-18 receptor beta antibody
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