Indoleamine 2 3-dioxygenase 1 Antibody BIOTIN

General Information

Product

Indoleamine 2, 3-dioxygenase 1 Antibody BIOTIN

Description

BIOTIN-Conjugated Indoleamine 2,3-dioxygenase 1 Antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 100-150 on human Indoleamine 2,3-dioxygenase 1 protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.5-1.5 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

BIOTIN-Conjugated

Purification Method

Immobilized antigen affinity chromatography

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:50,000

Immunoprecipitation

1:200

Western Blot

1:2,500-1:5,000

Protein

Uniprot #

P14902

Subcellular Location

cytosol

Expression

Expressed in mature dendritic cells located in lymphoid organs (including lymph nodes, spleen, tonsils, Peyers's patches, the gut lamina propria, and the thymic medulla), in some epithelial cells of the female genital tract, as well as in endothelial cells of term placenta and in lung parenchyma (PubMed:25691885). Weakly or not expressed in most normal tissues, but mostly inducible in most tissues (PubMed:25691885). Expressed in more than 50% of tumors, either by tumoral, stromal, or endothelial cells (expression in tumor is associated with a worse clinical outcome) (PubMed:18418598). Not overexpressed in tumor-draining lymph nodes (PubMed:26155395, PubMed:25691885).

Structure

Belongs to the indoleamine 2,3-dioxygenase family.

Alternative Nomenclature

3-dioxygenase antibody

I23O1_HUMAN antibody

IDO antibody

IDO1 antibody

INDO antibody

indolamine 2,3 dioxygenase antibody

Indole 2 3 dioxygenase antibody

indoleamine 2 3 dioxygenase 1 antibody

indoleamine 2 3 dioxygenase antibody

Indoleamine 2,3-dioxygenase 1 antibody

Indoleamine pyrrole 2 3 dioxygenase antibody

Indoleamine-pyrrole 2 antibody