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General Information
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Product
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Inhibin alpha Peptide
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Description
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Antigenic Blocking Peptide Inhibin alpha chain; Flags Antibody Mid Region
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Verified Applications
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Immunodepletion, Immunocompetition
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Peptide Description
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Synthetic peptide
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Physical Properties
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Quantity
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250 µg
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Volume
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100 µl
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Form
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Antigenic Blocking Peptide
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Determinant
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Mid Region
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Storage
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-20⁰C for long term storage
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Application Protocol
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Competition/Depletion assay
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Refer to competition assay protocol
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Protein
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Uniprot #
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P05111
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Overview
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Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone
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Molecular Function
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Cytokine activity, hormone activity, growth factor activity, receptor binding
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Subcellular Location
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Secreted
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Expression
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Originally found in ovary (granulosa cells) and testis (Sertoli cells), but widely distributed in many tissues including brain and placenta. In adrenal cortex expression is limited to the zona reticularis and the innermost zona fasciculata in the normal gland, extending centripetally into the zona fasciculata in hyperplasia. Also found in adrenocortical tumors. Also expressed in prostate epithelium of benign prostatic hyperplasia, in regions of basal cell hyperplasia and in nonmalignant regions of high grade prostate cancer. Only circulating inhibin B is found in male, whereas circulating inhibins A and B are found in female.
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Alternative Nomenclature
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A inhibin subunit precursor antibody
IHA antibody
inhA antibody
Inhibin alpha chain antibody
Inhibin alpha chain precursor antibody
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Inhibin alpha Antibody
Inhibin alpha Antibody FITC
Inhibin alpha Antibody BIOTIN
Inhibin alpha Positive Control
