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General Information
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Product
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MEK1 Peptide
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Description
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Antigenic Blocking Peptide Mitogen-activated protein kinase kinase 1 Antibody
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Verified Applications
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Immunodepletion, Immunocompetition
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Peptide Description
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Synthetic peptide taken within amino acid region 300-350 on human Mitogen-activated protein kinase kinase 1.
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Physical Properties
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Quantity
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250 µg
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Volume
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100 µl
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Form
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Antigenic Blocking Peptide
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Storage
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-20⁰C for long term storage
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Application Protocol
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Competition/Depletion assay
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Refer to competition assay protocol
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Protein
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Uniprot #
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Q02750
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Overview
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Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Binding of extracellular ligands such as growth factors, cytokines and hormones to their cell-surface receptors activates RAS and this initiates RAF1 activation.
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Molecular Function
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Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase
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Subcellular Location
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Cytoplasm, Cytoskeleton, Membrane, Nucleus
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Expression
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Widely expressed, with extremely low levels in brain.
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Structure
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The proline-rich region localized between residues 270 and 307 is important for binding to RAF1 and activation of MAP2K1/MEK1.
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Alternative Nomenclature
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Dual specificity mitogen activated protein kinase kinase 1 antibody
ERK activator kinase 1 antibody
MAP kinase/Erk kinase 1 antibody
MAP2K1 antibodyMAPKK 1 antibody
MAPKK1 antibody
MEKK1 antibody
Mitogen activated protein kinase kinase 1 antibody
MKK1 antibodyPRKMK1 antibody
Protein kinase mitogen activated, kinase 1 antibody
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MAP2K1 Antibody
MAP2K1 Antibody BIOTIN
MAP2K1 Antibody FITC
