Netrin 1 Blocking Peptide

General Information

Product

Netrin 1 Peptide

Verified Applications

Immunocompetition, Immunodepletion

Peptide Description

Synthetic peptide taken within amino acid region 250-300 on human Netrin-1 protein.

Accession #

NCBI: NP_004813.2

Physical Properties

Quantity

250 µg

Volume

100 µl

Form

Antigenic Blocking Peptide

Storage

-20⁰C for long term storage

Application Protocol

Competition/Depletion assay

Refer to competition assay protocol

Protein

Uniprot #

O95631

Overview

Netrins control guidance of CNS commissural axons and peripheral motor axons; serve as a survival factor via its association with its receptors which prevent the initiation of apoptosis;Involved in tumorigenesis by regulating apoptosis.

Subcellular Location

Extracellular matrix, Secreted

Expression

highest levels in heart, small intestine, colon, liver and prostate. Reduced expression in brain tumors and neuroblastomas. Expressed in epididymis (at protein level).

Alternative Nomenclature

epididymis tissue protein Li 131P antibody

Netrin 1, mouse, homolog of antibody

Netrin 1-like antibody

Ntn 1 antibody

Unc6 antibody