PACAP Blocking Peptide

Product no.: P-PACA
$155.00


General Information

 

 

Product

 

PACAP Peptide

Description

Antigenic Blocking Peptide Pituitary adenylate cyclase-activating polypeptide

Verified Applications

Immunodepletion, Immunocompetition

Immunogen

Synthetic peptide taken within amino acid region 125-176 on human Pituitary adenylate cyclase-activating polypeptide protein.


Physical Properties

 

 

Quantity

 

250 µg

Volume

100 µl

Form

Antigenic Blocking Peptide

Storage

-20C for long term storage


Application Protocol

Competition/Depletion assay

Refer to competition assay protocol


Protein

 

Uniprot #

 

P18509

Overview

Binding to its receptor activates G proteins and stimulates adenylate cyclase in pituitary cells. Promotes neuron projection development through the RAPGEF2/Rap1/B-Raf/ERK pathway. In chromaffin cells, induces long-lasting increase of intracellular calcium concentrations and neuroendocrine secretion. Involved in the control of glucose homeostasis, induces insulin secretion by pancreatic beta cells.

Molecular Function

neuropeptide hormone activity

peptide hormone receptor binding

pituitary adenylate cyclase activating polypeptide activity

pituitary adenylate cyclase-activating polypeptide receptor binding

receptor binding

signal transducer activity, downstream of receptor

Subcellular Location

Secreted

Expression

Interacts with ADCYAP1R1 (via N-terminal extracellular domain).

Structure

Belongs to the glucagon family.

Alternative Nomenclature

adenylate cyclase activating polypeptide 1 (pituitary) antibody

PACAP antibody

PACAP-related peptide antibody

Pituitary adenylate cyclase-activating polypeptide 27 antibody

Pituitary adenylate cyclase-activating polypeptide 38 antibody

Pituitary adenylate cyclase-activating polypeptide antibody

prepro-PACAP antibody

PRP-48 antibody

   

Protein information supplied by UniProt.

 

Accessories

Product Note Status Price
PACAP Antibody PACAP Antibody
PACA-101AP $285.00 *
PACAP Antibody BIOTIN PACAP Antibody BIOTIN
PACA-BIOTIN $375.00 *
PACAP Antibody FITC PACAP Antibody FITC
PACA-FITC $375.00 *
PACAP Positive Control PACAP Positive Control
PC-PACA $200.00 *
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