PACAP Positive Control

Product no.: PC-PACA

$200.00

Description

General Information
Product	PACAP Positive Control
Description	Western Blot Positive Control Pituitary adenylate cyclase-activating polypeptide
Verified Applications	WB
Immunogen	Purfied protein.
Physical Properties
Quantity	5 Applications
Volume	Inquire
Form	Western Blot Positive Control
Storage	-20⁰C for long term storage
Application Protocol
Western Blot	1:2,500-1:5,000
Protein
Uniprot #	P18509
Overview	Binding to its receptor activates G proteins and stimulates adenylate cyclase in pituitary cells. Promotes neuron projection development through the RAPGEF2/Rap1/B-Raf/ERK pathway. In chromaffin cells, induces long-lasting increase of intracellular calcium concentrations and neuroendocrine secretion. Involved in the control of glucose homeostasis, induces insulin secretion by pancreatic beta cells.
Molecular Function	neuropeptide hormone activity peptide hormone receptor binding pituitary adenylate cyclase activating polypeptide activity pituitary adenylate cyclase-activating polypeptide receptor binding receptor binding signal transducer activity, downstream of receptor
Subcellular Location	Secreted
Expression	Interacts with ADCYAP1R1 (via N-terminal extracellular domain).
Structure	Belongs to the glucagon family.
Alternative Nomenclature	adenylate cyclase activating polypeptide 1 (pituitary) antibody PACAP antibody PACAP-related peptide antibody Pituitary adenylate cyclase-activating polypeptide 27 antibody Pituitary adenylate cyclase-activating polypeptide 38 antibody Pituitary adenylate cyclase-activating polypeptide antibody prepro-PACAP antibody PRP-48 antibody

Protein information supplied by UniProt.