PAR2 Positive Control

General Information

Product

PAR2 Positive Control

Description

Western Blot Positive Control Proteinase-activated receptor 2

Verified Applications

WB

Immunogen

Purified Protein

Accession #

NCBI:  NP_032000.3

Physical Properties

Quantity

5 Applications

Volume

Inquire

Form

Western Blot Positive Control

Storage

-20⁰C for long term storage

Application Protocol

Western Blot

1:250

Protein

Uniprot #

P55086

Overview

Receptor for the MIP-3-beta chemokine. Probable mediator of EBV effects on B-lymphocytes or of normal lymphocyte functions.

Molecular Function

G-protein coupled receptor, Receptor, Transducer

Subcellular Location

Cell membrane; Multi-pass membrane protein

Expression

Expressed in various lymphoid tissues and activated B- and T-lymphocytes, strongly up-regulated in B-cells infected with Epstein-Barr virus and T-cells infected with herpesvirus 6 or 7.

Structure

Interacts with TLR4, COPS5 and TMED2.  Also interacts with GNAQ, GNA11, GNA12, GNA13, and GNA14.

Alternative Nomenclature

Coagulation factor II receptor like 1 

Coagulation factor II thrombin receptor like 1 

F2RL1 

G protein coupled receptor 11 

GPR11 

PAR 2 

Proteinase activated receptor 2

Thrombin receptor like 1