PDE10A2 Positive Control

General Information

Product

PDE10A2 Positive Control

Verified Applications

WB

Immunogen

Purified Protein

Accession #

GenBank: AAD32596.1

Physical Properties

Quantity

5 Applications

Volume

Inquire

Form

Western Blot Positive Control

Storage

-20⁰C for long term storage

Application Protocol

Western Blot

1:500

Protein

Uniprot #

Q9Y233

Overview

Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. Can hydrolyze both cAMP and cGMP, but has higher affinity for cAMP and is more efficient with cAMP as substrate.

Molecular Function

Hydrolase, metal-ion binding, cGMP binding

Subcellular Location

Cytoplasm

Expression

Abundant in the putamen and caudate nucleus regions of brain and testis, moderately expressed in the thyroid gland, pituitary gland, thalamus and cerebellum.

Structure

Homodimer

Alternative Nomenclature

5''-cyclic phosphodiesterase 10A antibody

cAMP and cAMP inhibited cGMP 3'5' cyclic phosphodiesterase 10A antibody

cAMP and cAMP-inhibited cGMP 3'' antibody

FLJ11894 antibody

HSPDE10A antibody

Phosphodiesterase 10A antibody