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General Information
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Product
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PDE11A3 Antibody FITC-Conjugated
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Description
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FITC-Conjugated Phosphodiesterase 11A3 Antibody
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Verified Applications
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ELISA, IMM, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human, Mouse, Rat
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Immunogen
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Synthetic peptide unique to PDE11A3 variant
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Accession #
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GenBank: AB038041.1
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.68 µg/µl in antibody stabilization buffer
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Form
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FITC-Conjugated
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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DB
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1:10,000
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ELISA
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1:10,000
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Immunoprecipitation
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1:250
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Western Blot
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1:500
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Protein
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Uniprot #
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Q9HCR9
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Overview
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Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides cAMP and cGMP. Catalyzes the hydrolysis of both cAMP and cGMP to 5'-AMP and 5'-GMP, respectively.
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Molecular Function
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Hydrolase, metal-ion binding, cGMP binding
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Subcellular Location
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Cytoplasm
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Expression
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Isoform 1 is present in prostate, pituitary, heart and liver. It is however not present in testis nor in penis, suggesting that weak inhibition by Tadalafil is not relevant (at protein level). Isoform 2 may be expressed in testis. Isoform 4 is expressed
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Alternative Nomenclature
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PDE11A antibody
PDE11A3 antibody
PPNAD2 antibody
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PDE11A3 Antibody
PDE11A3 Blocking Peptide
PDE11A3 Antibody BIOTIN
PDE11A3 Positive Control
