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General Information
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Product
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PDE11A4 Antibody Western Blot Positive Control
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Description
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Western Blot Positive Control Phosphodiesterase 11A4 Antibody
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Verified Applications
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WB
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Immunogen
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Purified Protein
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Accession #
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GenBank: BAB62712.1
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Physical Properties
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Quantity
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5 Applications
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Volume
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Inquire
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Form
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Western Blot Positive Control
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Storage
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-20⁰C for long term storage
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Application Protocol
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Western Blot
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1:500
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Protein
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Uniprot #
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Q9HCR9
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Overview
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Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides cAMP and cGMP. Catalyzes the hydrolysis of both cAMP and cGMP to 5'-AMP and 5'-GMP, respectively.
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Molecular Function
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Hydrolase, 3', 5'-cyclic-GMP phosphodiesterase activity, cGMP binding
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Subcellular Location
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Cytoplasm
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Expression
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Isoform 1 is present in prostate, pituitary, heart and liver. It is however not present in testis nor in penis, suggesting that weak inhibition by Tadalafil is not relevant (at protein level). Isoform 2 may be expressed in testis. Isoform 4 is expressed i
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Alternative Nomenclature
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cGMP phosphodiesterase 11A antibody
Pde11a antibody
Pde11A2 antibody
Pde11A3 antibody
PDE11A4 antibody
Phosphodiesterase 11A antibody
PPNAD2 antibody
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PDE11A4 Antibody
PDE11A4 Antibody FITC
PDE11A4 Blocking Peptide
PDE11A4 Antibody BIOTIN
