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General Information
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Product
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PDE2A2 Peptide
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Description
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Antigenic Blocking Peptide Phosphodiesterase 2A2
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Verified Applications
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Immunodepletion, Immunocompetition
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Peptide Description
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Synthetic peptide corresponding to region within amino acids 1-50 on N-terminus of human PDE2A2 protein.
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Accession #
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NCBI: NP_001230713.1
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Physical Properties
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Quantity
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250 µg
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Volume
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100 µl
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Form
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Antigenic Blocking Peptide
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Determinant
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N-epitope
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Storage
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-20⁰C for long term storage
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Application Protocol
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Competition/Depletion assay
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Refer to competition assay protocol
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Protein
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Uniprot #
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O00408
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Overview
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Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes.
Isoform PDE2A2: Regulates Mitochondrial cAMP Levels and Respiration.
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Molecular Function
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Calcium channel activity, cAMP binding, cGMP binding, cGMP-stimulated cyclic-nucleotide phosphodiesterase activity; drug binding; metal ion binding; protein homodimerization activity; TPR domain binding
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Subcellular Location
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Mitochondrion matrix
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Expression
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Expressed in brain and to a lesser extent in heart, placenta, lung, skeletal muscle, kidney and pancreas.
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Structure
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Belongs to the cyclic nucleotide phosphodiesterase family. PDE2 subfamily.
Contains 2 GAF domains.
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Alternative Nomenclature
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Phosphodiesterase 2A 2
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PDE2A2 Positive Control
PDE2A2 Antibody
PDE2A2 Antibody BIOTIN
PDE2A2 Antibody FITC
