General Information
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Product
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PDE4A10 Peptide
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Description
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Antigenic Blocking Peptide Phosphodiesterase 4A10 C-epitope
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Verified Applications
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Immunocompetition, Immunodepletion
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Peptide Description
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Synthetic peptide taken within amino acid region 1-50 on PDE4A10 protein.
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Accession #
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GenBank: AAF14352
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Physical Properties
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Quantity
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250 µg
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Volume
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100 µl
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Form
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Antigenic Blocking Peptide
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Determinant
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C-epitope
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Storage
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-20⁰C for long term storage
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Application Protocol
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Competition/Depletion assay
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Refer to competition assay protocol
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Protein
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Uniprot #
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P27815
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Overview
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Hydrolyzes the second messenger cAMP which is a key regulator of many important physiological processes.
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Molecular Function
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cAMP
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Subcellular Location
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Isoform 1: perinuclear region, Isoform 2: ruffle membrane, Isoform 4: Peripheral membrane protein, Isoform 6: perinuclear region, Isoform 7: Membrane, Cytoplasm
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Expression
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Isoform 1 is widely expressed. Isoform 2 is abundant in liver, stomach, testis, thyroid and adrenal glands. It is also found in placenta, kidney, pancreas, ovary, uterus, skin, monocytes, mast cells, macrophages, as well as in bronchial smooth muscle. Iso
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Structure
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Belongs to cyclic nucleotide phosphodiesterase family. PDE4 subfamily
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Alternative Nomenclature
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5''-cyclic phosphodiesterase 4A10 antibody
PDE46 antibody
phosphodiesterase 4A10 cAMP specific antibody
phosphodiesterase isozyme 4A10 antibody
phosphodiesterase type 4A10 antibody
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