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General Information
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Product
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PDE4A8 Peptide
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Description
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Antigenic Blocking Peptide cAMP-specific 3',5'-cyclic phosphodiesterase 4A Antibody
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Verified Applications
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Immunodepletion, Immunocompetition
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Peptide Description
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Synthetic Peptide
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Physical Properties
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Quantity
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250 µg
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Volume
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100 µl
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Form
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Antigenic Blocking Peptide
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Storage
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-20⁰C for long term storage
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Application Protocol
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Competition/Depletion assay
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Refer to competition assay protocol
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Protein
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Uniprot #
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P27815
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Overview
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Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes.
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Molecular Function
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metal ion binding, 3',5'-cyclic-AMP phosphodiesterase activity, cAMP binding
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Subcellular Location
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Isoform 1: Cytoplasm, perinuclear region; Isoform 2: Cytoplasm, perinuclear region. Cell projection, ruffle membrane; Isoform 4: Peripheral membrane protein; Isoform 6: Cytoplasm; perinuclear region; Isoform 7: Cytoplasm, Membrane
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Expression
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Isoform 1 is widely expressed. Isoform 2 is abundant in liver, stomach, testis, thyroid and adrenal glands. It is also found in placenta, kidney, pancreas, ovary, uterus, skin, monocytes, mast cells, macrophages, as well as in bronchial smooth muscle. Iso
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Structure
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Isoform 1 interacts with LYN. Isoform 2 and isoform 6 interact weakly with LYN. Isoform 1, isoform 2 and isoform 6 interact with ARRB2.
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Alternative Nomenclature
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5''-cyclic phosphodiesterase 4A antibody
cAMP specific 3 5 cyclic phosphodiesterase 4A antibody
cAMP-specific 3'' antibody
DPDE2 antibody
dunce antibody
PDE46 antibody
PDE4A antibody
Phosphodiesterase 4 antibody
phosphodiesterase 4A cAMP specific antibody
phosphodiesterase E2 dunce homolog antibody
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PDE4A8 Antibody
PDE4A8 Antibody FITC
PDE4A8 Antibody BIOTIN
PDE4A8 Positive Control
