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General Information
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Product
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PDE4D2 Peptide
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Description
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Antigenic Blocking Peptide Phosphodiesterase 4D2 Antibody
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Verified Applications
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Immunodepletion, Immunocompetition
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Peptide Description
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Synthetic Peptide
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Physical Properties
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Quantity
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250 µg
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Volume
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100 µl
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Form
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Antigenic Blocking Peptide
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Storage
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-20⁰C for long term storage
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Application Protocol
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Competition/Depletion assay
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Refer to competition assay protocol
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Protein
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Overview
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Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes.
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Molecular Function
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Hydrolase, 3',5'-cyclic-AMP phosphodiesterase activity, cAMP binding
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Subcellular Location
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Apical cell membrane, Cytoplasm, Membrane
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Expression
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Expressed in colonic epithelial cells (at protein level). Widespread; most abundant in skeletal muscle. Isoform 6 is detected in brain. Isoform 8 is detected in brain, placenta, lung and kidney. Isoform 7 is detected in heart and skeletal muscle.
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Structure
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Homodimer for the long isoforms. Isoforms with truncated N-termini are monomeric. Isoform 3 is part of a ternary complex containing PRKAR2A, PRKAR2B and AKAP9. Interacts with PDE4DIP. Identified in a complex composed of RYR1, PDE4D, PKA, FKBP1A and protein phosphatase 1.
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Alternative Nomenclature
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cAMP specific 3',5' cyclic phosphodiesterase 4D antibody
DKFZp686M11213 antibody
cAMP-specific 3'' antibody
cyclic AMP phosphodiesterase antibody
DPDE 3 antibody
FLJ97311 antibody
HSPDE4D antibody
PDE43 antibody
PDE4DN2 antibody
Phosphodiesterase 4D, cAMP specific (dunce) antibody
Phosphodiesterase E3 dunce homolog Drosophila antibody
STRK 1 antibody
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PDE4D2 Antibody
PDE4D2 Antibody FITC
PDE4D2 Antibody BIOTIN
PDE4D2 Positive Control
