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General Information
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Product
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PDE4D4 Peptide
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Description
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Antigenic Blocking Peptide cAMP-specific phoshodiesterase HPDE4D3 variant C-epitope
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Verified Applications
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Immunodepletion, Immunocompetition
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Peptide Description
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Synthetic Peptide
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Accession #
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GenBank: EAW74861.1
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Physical Properties
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Quantity
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250 µg
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Volume
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100 µl
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Form
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Antigenic Blocking Peptide
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Determinant
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C-epitope
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Storage
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-20⁰C for long term storage
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Application Protocol
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Competition/Depletion assay
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Refer to competition assay protocol
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Protein
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Uniprot #
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Q08499
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Overview
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Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes.
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Molecular Function
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Hydrolase, 3',5'-cyclic-AMP phosphodiesterase activity, cAMP binding
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Subcellular Location
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Apical cell membrane, Cytoplasm, Membrane
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Expression
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Expressed in colonic epithelial cells (at protein level). Widespread; most abundant in skeletal muscle. Isoform 6 is detected in brain. Isoform 8 is detected in brain, placenta, lung and kidney. Isoform 7 is detected in heart and skeletal muscle.
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Structure
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Homodimer for the long isoforms. Isoforms with truncated N-termini are monomeric. Isoform 3 is part of a ternary complex containing PRKAR2A, PRKAR2B and AKAP9. Interacts with PDE4DIP. Identified in a complex composed of RYR1, PDE4D, PKA, FKBP1A and protein phosphatase 1 (PP1).
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Alternative Nomenclature
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cAMP specific 3',5' cyclic phosphodiesterase 4D antibody
DKFZp686M11213 antibody
5''-cyclic phosphodiesterase 4D antibody
cAMP specific 3' 5' cyclic phosphodiesterase 4D antibody
cAMP specific phosphodiesterase PDE4D6 antibody
DPDE3 antibody
Dunce like phosphodiesterase E3 antibody
FLJ97311 antibody
HSPDE4D antibody
PDE 43 antibody
Pde4d antibody
Drosophila antibody
STRK 1 antibody
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PDE4D4 Antibody
PDE4D4 Antibody FITC
PDE4D4 Antibody BIOTIN
PDE4D4 Positive Control
