PDE5A Antibody

Product no.: PD5A-101AP
$320.00


General Information

 

 

Product

 

PDE5A Antibody

Description

Affinity Purified cGMP-specific 3',5'-cyclic phosphodiesterase isoform 1 Antibody

Verified Applications

CM, ELISA, ICC/IF, IHC-P, IHC-Fr, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Pig, Rat

Immunogen

Synthetic peptide common to all PDE5A variants taken within amino acid region 120-170 on human PDE5A protein.

Specificity This antibody detects 99 and 89 kDa PDE5A proteins in various tissues. This antibody does not cross-react with other PDE family members.


Physical Properties

 

 

Quantity

 

100 µg

Volume

200 µl

Concentration

0.55-0.60 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20C for long term storage


Application Protocol

 

Confocal Microscopy

 

1:250

DB

1:10,000

ELISA

1:10,000

Immunocytochemistry

1:250

Immunofluorescence

1:250

Immunohistochemistry

1:250

Immunoprecipitation

1:250

Western Blot

1:500-1:1,000


Protein

 

Uniprot #

 

O76074

Overview

Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This phosphodiesterase catalyzes the specific hydrolysis of cGMP to 5'-GMP.

Molecular Function

Hydrolase, 3',5'-cyclic-GMP phosphodiesterase activity, cGMP binding

Subcellular Location

cytosol

Expression

Expressed in aortic smooth muscle cells, heart, placenta, skeletal muscle and pancreas and, to a much lesser extent, in brain, liver and lung.

Alternative Nomenclature

5''-cyclic phosphodiesterase antibody

CGB PDE antibody

cGMP binding cGMP specific 3' 5' cyclic nucleotide phosphodiesterase antibody

cGMP binding/cGMP specific phosphodiesterase antibody

cGMP specific 3'5' cyclic phosphodiesterase antibody

cGMP specific phosphodiesterase PDE5A2 antibody

cGMP specific phosphodiesterase type 5A antibody

cGMP-specific 3'' antibody

CN5A antibody

CN5N antibody

PDE 5 antibody

PDE 5A antibody

PDE5A1 antibody

Phosphodiesterase 5A antibody

Phosphodiesterase 5A cGMP specific antibody

Phosphodiesterase isozyme 5 antibody

   

Protein information supplied by UniProt

Accessories

Product Note Status Price
PDE5A Antibody FITC PDE5A Antibody FITC
PD5A-FITC $375.00 *
PDE5A Antibody BIOTIN PDE5A Antibody BIOTIN
PD5A-BIOTIN $375.00 *
PDE5A Blocking Peptide PDE5A Blocking Peptide
P-PD5A $155.00 *
HRP-Conjugated PDE5A Antibody HRP-Conjugated PDE5A Antibody
PD5A-HRP $375.00 *
PDE5A Positive Control PDE5A Positive Control
PC-PD5A $220.00 *
Display accessory details

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