PDE9A Positive Control

General Information

Product

PDE9A Positive Control

Description

Western Blot Positive Control High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A isoform a

Verified Applications

WB

Immunogen

Purified Protein

Accession #

NCBI:  NP_002597.1

Physical Properties

Quantity

5 Applications

Volume

Inquire

Form

Western Blot Positive Control

Storage

-20⁰C for long term storage

Application Protocol

Western Blot

Apply 15-20 µl per lane

Protein

Uniprot #

O76083

Overview

Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May have a role in muscle signal transduction.

Molecular Function

Hydrolase, 3', 5' -cyclic-GMP phosphodiesterase activity

Subcellular Location

Isoform PDE9A1: Cell projection, Cytoplasm, Golgi Apparatus, Endoplasmic reticulum, Isoform PDE9A2: Cell projection, Cytoplasm, Isoform PDE9A3: Cytoplasm, Endoplasmic Reticulum, Isoform PDE9A17: Cytoplasm, Endoplasmic reticulum

Expression

Expressed in all tissues examined (testis, brain, small intestine, skeletal muscle, heart, lung, thymus, spleen, placenta, kidney, liver, pancreas, ovary and prostate) except blood. Highest levels in brain, heart, kidney, spleen, prostate and colon. Isoform PDE9A12 is found in prostate.

Alternative Nomenclature

FLJ90181 antibody

HSPDE9A2 antibody

PDE 9A antibody

Pde9a antibody

Phosphodiesterase 9A antibody

phosphodiesterase PDE9A21 antibody