General Information |
|
Product |
Phospho-CACNB2 Antibody FITC |
Description |
FITC-Conjugated Voltage dependent L-type calcium channel subunit beta-2 Antibody |
Verified Applications |
Cell labeling, ELISA, IP, WB |
Host |
Rabbit |
Species Cross Reactivity |
Human, Mouse, Rat |
Immunogen |
Synthetic peptide taken within amino acid region 600-655 on rat CACNB2 protein. |
Accession # |
NCBI: NP_446303 |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.6 µg/µl in antibody stabilization buffer |
Form |
FITC-Conjugated |
Clonality |
Polyclonal |
Storage |
-20⁰C for long term storage |
|
|
Dot Blot |
1:10,000 |
ELISA |
1:10,000 |
Western Blot |
1:500 |
|
|
Uniprot # |
|
Overview |
The beta subunit of voltage-dependent calcium channel which contributes to calcium channel function by increasing peak calcium current, shifting the voltage dependencies fo activation and inactivation, modulating G-protein inhibition and controllin the alpha-1 subunit membrane targeting. |
Molecular Function |
Calcium; Transport; Ion transport |
Subcellular Location |
Cell membrane; Sacrolemma; Peripheral membrane protein, cytoplasmic side |
Expression |
Heart and brain. Lower expression in lung. |
Structure |
L-type channel is composed of four subunits: alpha-1, alpha-2, beta and gamma. |
Alternative Nomenclature |
AW060387 antibody Ca(V) beta 2 antibody CAB2 antibody CAVB2 antibody Cavbeta2 antibody Cchb2 antibody Lambert Eaton Myasthenic syndrome antigen antibody MYSB antibody |
Protein information supplied by UniProt
FabGennix Phospho-CACNB2 Antibody has been used in 1 Publication |
|
Fortalezas, Sofia, Dorinda Marques-da-Silva, and Carlos Gutierrez-Merino. "Methyl-β-Cyclodextrin Impairs the Phosphorylation of the β2 Subunit of L-Type Calcium Channels and Cytosolic Calcium Homeostasis in Mature Cerebellar Granule Neurons." International journal of molecular sciences 19.11 (2018): 3667. PMID30463327 |
Cell labeling, Western Blot; Rat |
Publishing research using PCCB2-140AP? Please let us know, we can cite the reference in this datasheet.
Product | Note | Status | Price | |
---|---|---|---|---|
|
PCCB2-140AP | |||
|
P-PCCB2 | |||
|
PCCB2-BIOTIN | |||
|
PC-PCCB2 | |||
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