|
General Information
|
|
|
Product
|
Phospho-JAK1 Peptide
|
|
Description
|
Antigenic Blocking Peptide Phosphorylated Tyrosine-protein kinase JAK1 Antibody
|
|
Verified Applications
|
Immunodepletion, Immunocompetition
|
|
Peptide Description
|
Synthetic peptide taken within amino acid region 1000-1050 on human JAK1 protein. Phosphorylated 1034 & 1035 tyrosine residues.
|
|
Physical Properties
|
|
|
Quantity
|
250 µg
|
|
Volume
|
100 µl
|
|
Form
|
Antigenic Blocking Peptide
|
| Modification |
Phosphorylated tyrosine 1034 & 1035. |
|
Storage
|
-20⁰C for long term storage
|
|
Application Protocol
|
|
Competition/Depletion assay
|
Refer to competition assay protocol
|
|
Protein
|
|
Uniprot #
|
P23458
|
|
Overview
|
Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway (PubMed:7615558). Kinase partner for the interleukin (IL)-2 receptor (PubMed:11909529).
|
|
Molecular Function
|
Kinase, Transferase, Tyrosine-protein kinase
|
|
Expression
|
Endomembrane system; Peripheral membrane protein
|
|
Structure
|
Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily.
Contains 1 FERM domain.
Contains 2 protein kinase domains.
Contains 1 SH2 domain.
|
|
Alternative Nomenclature
|
JAK 1
JAK 1A
JAK 1B
Janus kinase 1 (a protein tyrosine kinase)
Janus kinase 1
JTK3
Tyrosine protein kinase JAK1
|
| |
|
Phospho-JAK1 Positive Control
Phospho-JAK1 Antibody
Phospho-JAK1 Antibody BIOTIN
Phospho-JAK1 Antibody FITC
