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General Information
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Product
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RIC8A Antibody BIOTIN-Conjugated
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Description
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BIOTIN-Conjugated Synembryn-A isoform 1 Antibody
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Verified Applications
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ELISA, IMM, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human, Mouse
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Immunogen
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Synthetic peptide taken within amino acids 500-535 on RIC8A protein
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Accession #
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NCBI: NP_068751.4
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.60-0.75 µg/µl in antibody stabilization buffer
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Form
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BIOTIN-Conjugated
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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Immunoprecipitation
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1:200
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Western Blot
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1:250
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Protein
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Uniprot #
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Q9NPQ8
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Overview
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Guanine nucleotide exchange factor (GEF) which can activate some G-alpha proteins. Able to activate GNAI1, GNAO1 and GNAQ, but not GNAS by exchanging bound GDP for free GTP.
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Molecular Function
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guanyl-nucleotide exchange factor activity, Guanine-nucleotide releasing factor
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Subcellular Location
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Interacts with GDP-bound G alpha proteins GNAI1, GNAO1 and GNAQ, and with GNA13 with lower affinity. Does not interact with G-alpha proteins when they are in complex with subunits beta and gamma.
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Alternative Nomenclature
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Protein Ric-8A antibody
resistance to inhibitors of cholinesterase 8 homolog A (C. elegans) antibody
RIC8 antibody
Synembryn-A antibody
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RIC8A Blocking Peptide
RIC8A Antibody
RIC8A Antibody FITC
RIC8A Positive Control
