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General Information
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Product
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SIRT7 Positive Control
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Description
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Western Blot Positive Control Sirtuin (silent mating type information regulation 2 homolog) 7
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Verified Applications
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WB
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Immunogen
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Purified Protein
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Accession #
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Gen Bank: AAH17305.1
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Physical Properties
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Quantity
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5 Applications
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Volume
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Inquire
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Form
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Western Blot Positive Control
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Storage
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-20⁰C for long term storage
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Application Protocol
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Western Blot
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1:500
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Protein
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Uniprot #
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Q9NRC8
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Overview
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NAD-dependent protein deacetylase that specifially mediates deacetylation of histone H3 at 'Lys-18'. Displays selectivity for a single histone mark, H3K18Ac, directly linked to control of gene expression.
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Molecular Function
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Chromatin binding, NAD+ binding, NAD-dependent histone deacetylase activity (H3-K18 specific), metal ion binding
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Subcellular Location
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Cytoplasm, nucleus, nucleolus. (Note: Located close to the nuclear membrane when in cytoplasm. Associated with chromatin. Associated with rDNA promoter and transcribed region. Associated with nucleolar organizer regions during mitosis.
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Expression
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Detected in liver, spleen and testis. Detected in embryos.
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Structure
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Belongs to the Sirtuin Family. Class IV subfamily. Contains 1 deacetylase sirtuin-type domain.
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Alternative Nomenclature
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NAD dependent deacetylase sirtuin 7 antibody
Regulatory protein SIR2 homolog 7 antibody
Silent mating type information regulation 2 homolog antibody
SIR2 L7 antibody
SIR2 like protein 7 antibody
Sir2 related protein type 7 antibody
SIRT7 antibody
Sirtuin 7 antibody
Sirtuin type 7 antibody
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SIRT7 Antibody
SIRT7 Antibody BIOTIN
SIRT7 Blocking Peptide
SIRT7 Blocking Peptide
SIRT7 Antibody
SIRT7 Antibody FITC
SIRT7 Antibody FITC
SIRT7 Antibody BIOTIN
