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General Information
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Product
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SPHK1 Antibody
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Description
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Affinity Purified Sphingosine kinase 1 Antibody
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Verified Applications
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ELISA, IHC, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human, Monkey, Mouse, Rat
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Immunogen
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Synthetic peptide taken within amino acid region 50-100 on human SPHK1 protein.
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Accession #
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GenBank: CAM17117.1
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.64-0.72 µg/µl in antibody stabilization buffer
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Form
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Affinity Purified
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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DB
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1:10,000
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ELISA
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1:10,000
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| Immunohistochemistry |
1:100 |
| Immunoprecipitation |
1:200 |
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Western Blot
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1:500
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Protein
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Uniprot #
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Q8CI15
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Overview
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Catalyzes the phosphorylation of sphingosine to form sphingosine 1-phosphate (SPP), a lipid mediator with both intra- and extracellular functions. Also acts on D-erythro-sphingosine and to a lesser extent sphinganine, but not other lipids, such as D,L-threo-dihydrosphingosine, N,N-dimethylsphingosine, diacylglycerol, ceramide, or phosphatidylinositol.
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Molecular Function
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ATP binding, calmodulin binding, DNA binding, magnesium ion binding, NAD+kinase activity, sphinganine kinase activity
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Subcellular Location
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Cytoplasm, nucleus, cell membrane
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Alternative Nomenclature
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SK1 antibody
Sphingosine Kinase 1 antibody
SPHK 1 antibody
SPHK antibody
SPK antibody
SPK 1 antibody
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SPHK1 Antibody FITC
SPHK1 Antibody BIOTIN
SPHK1 Blocking Peptide
SPHK1 Positive Control
