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General Information
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Product
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TRPM8 Antibody Affinity Purified
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Description
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Affinity Purified Transient receptor potential cation channel subfamily M member 8 Antibody
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Verified Applications
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ELISA, WB
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Host
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Rabbit
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Species Cross Reactivity
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Rat, Mouse
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Immunogen
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Synthetic peptide corresponding to unique amino acid sequence on TRPM8 protein.
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Accession #
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NCBI: NP_599198.2
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.6 µg/µl in antibody stabilization buffer
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Form
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Affinity Purified
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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DB
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1:10,000
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ELISA
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1:10,000
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Western Blot
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1:500
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Protein
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Uniprot #
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Q8R455
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Overview
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Involved in detection of sensations such as coolness, activated by icilin, eucalyptol, menthol, cold and modulation of intracellular pH
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Molecular Function
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Calcium channel activity
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Subcellular Location
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cell membrane, multi-pass membrane protein, membrane raft. (Note: Localizes to membrane rafts but is also loated in the cell membrane outside of these regions where channel response to cold is enhanced compared to membrane rafts)
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Expression
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Expressed in dorsal root and trigeminal ganglia. Specifically expressed in a subset of sensory neurons, including cold-sensitive neurons in trigeminal neurons.
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Alternative Nomenclature
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Long transient receptor potential channel 6 antibody
LTrpC6 antibody
Short form of the TRPM8 cationic channel antibody
Transient receptor potential cation channel subfamily M member 8 antibody
Transient receptor potential p8 antibody
TRPP8 antibody
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TRPM8 Antibody FITC
TRPM8 Antibody BIOTIN
TRPM8 Blocking Peptide
TRPM8 Positive Control
