TRPM8 Positive Control

General Information

Product

TRPM8 Antibody Western Blot Positive Control

Description

Western Blot Positive Control Transient receptor potential cation channel subfamily M member 8 Antibody

Verified Applications

WB

Immunogen

Purified Protein

Accession #

NCBI:  NP_599198.2

Physical Properties

Quantity

5 Applications

Volume

Inquire

Form

Western Blot Positive Control

Storage

-20⁰C for long term storage

Application Protocol

Western Blot

1:500

Protein

Uniprot #

Q8R455

Overview

Involved in detection of sensations such as coolness, activated by icilin, eucalyptol, menthol, cold and modulation of intracellular pH

Molecular Function

Calcium channel activity

Subcellular Location

cell membrane, multi-pass membrane protein, membrane raft. (Note: Localizes to membrane rafts but is also loated in the cell membrane outside of these regions where channel response to cold is enhanced compared to membrane rafts)

Expression

Expressed in dorsal root and trigeminal ganglia. Specifically expressed in a subset of sensory neurons, including cold-sensitive neurons in trigeminal neurons.

Alternative Nomenclature

Long transient receptor potential channel 6 antibody

LTrpC6 antibody

Short form of the TRPM8 cationic channel antibody

Transient receptor potential cation channel subfamily M member 8 antibody

Transient receptor potential p8 antibody

TRPP8 antibody