TYRO3 Blocking Peptide

General Information

Product

TYRO3 Peptide

Description

Antigenic Blocking Peptide Tyrosine-protein kinase receptor TYRO3  

Verified Applications

Immunocompeition, Immunodepletion

Peptide Description

Synthetic peptide taken within amino acid reigon 800-850 on human Tyrosine-protein kinase receptor TYRO3 protein.

Accession #

NCBI:  NP_006284.2

Physical Properties

Quantity

250 µg

Volume

100 µl

Form

Antigenic Blocking Peptide

Storage

-20⁰C for long term storage

Application Protocol

Competition/Depletion assay

Refer to competition assay protocol

Protein

Uniprot #

Q06418

Overview

Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to several ligands including TULP1 or GAS6. Regulates many physiological processes including cell survival, migration and differentiation.

Molecular Function

Kinase, Receptor, Transferase, Tyrosine-protein kinase

Subcellular Location

Cell membrane; Single-pass Type I membrane protein

Expression

Abundant in the brain and lower levels in other tissues.

Structure

Monomer and homodimer. Interacts (via N-terminus) with extracellular ligands TULP1 and GAS6. Interacts with PIK3R1; this interaction increases PI3-kinase activity.

Alternative Nomenclature

Brt antibody

BYK antibody

DTK antibody

RSE antibody

SKY antibody

Tif antibody

TYRO3 antibody

Tyrosine-protein kinase byk antibody

Tyrosine-protein kinase DTK antibody

Tyrosine-protein kinase receptor TYRO3 antibody

Tyrosine-protein kinase RSE antibody

Tyrosine-protein kinase SKY antibody