General Information |
|
Product |
Topoisomerase II alpha Antibody Western Blot Positive Control |
Description |
Western Blot Positive Control DNA topoisomerase (ATP-hydrolysing) Antibody |
Verified Applications |
WB |
Immunogen |
Purified Protein |
Accession # |
GenBank: CAA09762.1 |
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|
Quantity |
5 Applications |
Volume |
Inquire |
Form |
Western Blot Positive Control |
Storage |
-20⁰C for long term storage |
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Western Blot |
1:500 |
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Uniprot # |
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Overview |
Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Essential during mitosis and meiosis for proper segregation of daughter chromosomes. |
Molecular Function |
Isomerase, Topoisomerase, ATP binding |
Subcellular Location |
Cytoplasm, Nucleus |
Structure |
Homodimer. Interacts with COPS5. Interacts with RECQL5; this stimulates DNA decatenation. Interacts with SETMAR; stimulates the topoisomerase activity. |
Alternative Nomenclature |
alpha isozyme antibody ATP hydrolyzing DNA topoisomerase II alfa antibody DNA gyrase antibody DNA topoisomerase 2 alpha antibody DNA topoisomerase II 170 kD antibody DNA topoisomerase II alpha isozyme antibody TOP2 antibody TOP2A antibody Topoisomerase DNA II alpha 170kDa antibody TP2A antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
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TOPO2A-201AP | |||
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TOPO2A-FITC | |||
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P-TOPO2A | |||
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TOPO2A-BIOTIN | |||
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