General Information
|
|
Product
|
LILRB3 Positive Control
|
Description
|
Western Blot Positive Control Leukocyte immunoglobulin-like receptor subfamily B member 3 precursor Antibody
|
Verified Applications
|
WB
|
Immunogen
|
Purified Protein
|
Accession #
|
NCBI: NP_035225.2
|
Physical Properties
|
|
Quantity
|
5 Applications
|
Volume
|
Inquire
|
Form
|
Western Blot Positive Control
|
Storage
|
-20⁰C for long term storage
|
Application Protocol
|
Western Blot
|
1:500
|
Protein
|
Uniprot #
|
P97484
|
Overview
|
May act as receptor for class I MHC antigens. Becomes activated upon coligation of LILRB3 and immune receptors, such as FCGR2B and the B-cell receptor. Down-regulates antigen-induced B-cell activation by recruiting phosphatases to its immunoreceptor tyrosine-based inhibitor motifs (ITIM).
|
Subcellular Location
|
Cell membrane, single-pass type I membrane protein
|
Expression
|
Detected in macrophages, splenocytes and B lymphocytes (at protein level). Detected in macrophages, mast cells, splenocytes, peritoneal cells and natural killer cells.
|
Alternative Nomenclature
|
CD85 antigen like family member A antibody
HL9 antibody
IL T5 antibody
Immunoglobulin like transcript 5 antibody
LIR 3 antibody
MGC138403 antibody
Monocyte inhibitory receptor HL9 antibody
PIRB antibody
|
|
|