General Information |
|
Product |
DRP1 Antibody BIOTIN |
Description |
BIOTIN-conjugated Dynamin-related Protein 1 Antibody |
Verified Applications |
ELISA, ICC, IF, IHC, IP, WB |
Host |
Rabbit |
Species Cross Reactivity |
D. Melanogaster, Human, Mouse, Rat |
Immunogen |
Synthetic peptide within 450-490 on human DRP1 protein |
Accession # |
GenBank: BAC06576.1 |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.55-0.68 µg/µl in antibody stabilization buffer |
Immunoglobulin |
IgG |
Form | BIOTIN-conjugated |
Clonality |
Polyclonal |
Storage |
-20°C for long term storage |
|
|
ELISA |
1:10,000 |
Immunocytochemistry |
1:100 |
Immunofluorescence |
1:100 |
Immunohistochemistry |
1:100 |
Immunoprecipitation |
1:200 |
Western Blot |
1:450 |
|
|
Uniprot # |
|
Overview |
Functions in mitochondrial and peroxisomal division. Mediates membrane fission through oligomerization into membrane-associated tubular structures that wrap around the scission site to constrict and sever the mitochondrial membrane through a GTP hydrolysis-dependent mechanism. |
Molecular Function |
GTP-binding, Lipid-binding, Nucleotide-binding |
Subcellular Location |
Golgi apparatus; Peripheral membrane protein; peroxisome; Mitochondrion outer membrane; Clathrin-coated pit; synaptic vesicle membrane |
Expression |
Expressed in the cerebellum and in several regions of the cerebrum and diencephalon |
Structure |
Homotetramer; dimerizes through the N-terminal GTP-middle region of one molecule binding to the GED domain of another DNM1L molecule. Oligomerizes in a GTP-dependent manner to form membrane-associated tubules with a spiral pattern. Can also oligomerize to form multimeric ring-like structures. |
Alternative Nomenclature |
DLP1 antibody dnm1l antibody Dnm1p/Vps1p-like protein antibody dnml1 antibody DRP1 antibody DVLP antibody Dymple antibody Dynamin 1 like antibody Dynamin family member proline-rich carboxyl-terminal domain less antibody Dynamin like protein antibody Dynamin related protein 1 antibody Dynamin-like protein 4 antibody Dynamin-related protein 1 antibody DYNIV 11 antibody EMPF antibody FLJ41912 antibody HdynIV antibody VPS1 antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
|
DRP1-101AP | |||
|
P-DRP1 | |||
|
DRP1-FITC | |||
|
PC-DRP1 | |||
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