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General Information
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Product
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14-3-3 sigma Positive Control
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Description
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Western Blot Positive Control 14-3-3 protein sigma / STRATIFIN / SFN
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Verified Applications
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WB
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Physical Properties
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Quantity
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5 Applications
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Volume
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Inquire
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Form
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Western Blot Positive Control
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Storage
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-20⁰C for long term storage
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Application Protocol
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Western Blot
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1:2,500-1:5,000
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Protein
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Uniprot #
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P31947
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Overview
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Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway. May also regulate MDM2 autoubiquitination and degradation and thereby activate p53/TP53.1 Publication
p53-regulated inhibitor of G2/M progression.
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Molecular Function
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cadherin binding
identical protein binding
phosphoprotein binding
protein domain specific binding
protein kinase binding
protein kinase C inhibitor activity
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Subcellular Location
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Nucleus, secreted
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Expression
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Present mainly in tissues enriched in stratified squamous keratinizing epithelium.
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Structure
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Belongs to the 14-3-3 family.
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Alternative Nomenclature
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14 3 3 protein sigma antibody
1433S_HUMAN antibody
Epithelial cell marker protein 1 antibody
Er antibody
HME 1 antibody
Mkrn3 antibody
Mme1 antibody
RP23 137L22.11 antibody
SFN antibody
SFN protein antibody
Stratifin antibody
YWHAS antibody
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14-3-3 sigma Antibody
14-3-3 sigma Antibody BIOTIN
14-3-3 sigma Antibody FITC
14-3-3 sigma Blocking Peptide
