General Information
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Product
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Cannabinoid Receptor II Antibody
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Description
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Affinity Purified Cannabinoid receptor 2 Antibody
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Verified Applications
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ELISA, IHC, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human, Mouse, Rat
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Immunogen
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Synthetic peptide taken within amino acid region 300-350 on mouse CB2 Receptor protein common to both CB2L and CB2S.
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.61-0.63 µg/µl in antibody stabilization buffer
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Form
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Affinity Purified
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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DOT Blot
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1:10,000
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ELISA
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1:10,000
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Immunohistochemistry |
1:50-1:150 |
Immunoprecipitation |
1:200 |
Western Blot
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1:500
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Protein
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Uniprot #
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P47936
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Overview
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Heterotrimeric GPCR for endocannabinoid 2-arachidonoylglycerol mediating inhibition of Adenylate cyclase. Functions in inflammatory response, nociceptive transmission and bone homeostasis.
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Molecular Function
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Inflammatory response; GPCR; Receptor; Transducer
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Subcellular Location
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Cell membrane; Multi-pass membrane protein; Dendrite; Perikaryon
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Expression
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Cells of hematopoietic origin. Expressed in skin in suprabasal layers and hair follices. In brain by neurons and glial cells. Expressed in osteoblasts, osteocytes and osteoclasts.
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Structure
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belongs to G-protein coupled receptor 1 family
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Alternative Nomenclature
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Cannabinoid receptor 2 macrophage antibody
CB 2 antibody
CNR2 antibody
CX 5 antibody
testis-dominant CNR2 isoform CB2 antibody
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