General Information
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Product
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DCC Peptide
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Description
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Antigenic Blocking Peptide Netrin Receptor DCC Antibody
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Verified Applications
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Immunodepletion, Immunocompetition
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Peptide Description
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Synthetic peptide taken within amino acid region 1330-1380 on rat DCC protein.
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Physical Properties
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Quantity
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250 µg
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Volume
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100 µl
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Form
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Antigenic Blocking Peptide
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Storage
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-20°C for long term storage
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Application Protocol
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Competition/Depletion assay
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Refer to competition assay protocol
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Protein
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Uniprot #
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P43146
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Overview
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Receptor for netrin required for axon guidance; may trigger signaling for axon repulsion; acts as a dependence receptor required for apoptosis induction; tumor suppressor gene.
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Molecular Function
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netrin receptor activity; transcription coactivator activity; transmembrane signaling receptor activity; Developmental protein
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Subcellular Location
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axon; cytosol; plasma membrane
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Expression
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Found in axons of the central and peripheral nervous system; differentiated cell types of the intestine
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Structure
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Belongs to the immunoglobulin superfamily. DCC family; Contains 6 fibronectin type-III domains; Contains 4 Ig-like C2-type (immunoglobulin-like) domains
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Alternative Nomenclature
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Colorectal cancer related chromosome sequence 18 antibody
CRC 18 antibody
CRCR 1 antibody
DCC antibody
Deleted in colorectal cancer protein antibody
Immunoglobulin superfamily DCC subclass member 1 antibody
Netrin receptor DCC antibody
Tumor suppressor protein DCC antibody
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