EPAC2 Antibody

Product no.: EPAC-201AP

$320.00

General Information
Product	Epac2 Antibody
Description	Affinity Purified Rap Guanine Nucleotide Exchange Factor 3 Antibody
Verified Applications	CM, ELISA, ICC/IF, IHC, IP, WB
Host	Rabbit
Species Cross Reactivity	Human, Mouse, Rabbit, Rat
Immunogen	Synthetic peptide corresponding to amino acids 743-762 of Epac2 protein. Sequence: CPREQFDSLTPLPEQEGPT
Specificity	This antibody does not cross react with other Epac family proteins.
Physical Properties
Quantity	100 µg
Volume	200 µl
Concentration	0.67 µg/µl in antibody stabilization buffer
Form	Affinity Purified
Clonality	Polyclonal
Storage	-20⁰C for long term storage
Application Protocol
Confocal Microscopy	1:200
DB	1:10,000
ELISA	1:10,000
Immunocytochemistry	1:200
Immunofluorescence	1:200
Immunohistochemistry	1:200
Immunoprecipitation	1:200
Western Blot	1:500. Predicted molecular weight: 112 kDa
Protein
Uniprot #	Q9Z1C7
Overview	Guanine nucleotide exchange factor (GEF) for RAP1A, RAP1B and RAP2A small GTPases that is activated by binding cAMP. Seems not to activate RAB3A. Involved in cAMP-dependent, PKA-independent exocytosis through interaction with RIMS2.
Molecular Function	Guanine-nucleotide releasing factor
Subcellular Location	Cytoplasm; Membrane; Peripheral membrane protein
Structure	Interacts with RIMS1 and RIMS2. Probably part of a complex with RIMS2 and GTP-activated RAB3A.
Alternative Nomenclature	CAMP GEFII antibody cAMP regulated guanine nucleotide exchange factor II antibody CGEF2 antibody Epac 2 antibody Exchange protein directly activated by cAMP 2 antibody Nbla00496 antibody Putative protein product of Nbla00496 antibody Rap guanine nucleotide exchange factor (GEF) 4 antibody RAPGEF 4 antibody

Protein information supplied by UniProt

Fabgennix Epac2 Antibody has been used in 1 Publication

McPartlin, L.A., P.E. Visconti, and S.J. Bedford-Guaus. “Guanine-Nucleotide Exchange Factors (RAPGEF3/RAPGEF4) Induce Sperm Membrane Depolarization and Acrosomal Exocytosis in Capacitated Stallion Sperm.”Biology of Reproduction 85.1 (2011): 179–188. PMC3123385

Confocal Microscopy, Immunofluorescence, Western Blot; Horse, Mouse

Publishing research using EPAC-201AP? Please let us know, we can cite the reference in this datasheet.

Customer ratings for EPAC2 Antibody

Number of ratings: 1
Average rating: 4

Good
from Verified Customer on 01/04/2021

Western blot. Rabbit cell lysate- whole cell (pancreatic acini). 20µg rabbit pancreatic acini loaded on reduced denaturing (7.5%) gel. 5% BSA as blocking agent for 2 hours at 25°C.

All incoming ratings are posted by actual shop visitors / webshop customers and their content is checked by the operator by means of a visual inspection.