ETS1 Associated protein II Antibody

Product no.: TDP2-201AP

$285.00

Description

General Information
Product	ETS1 associated protein II Antibody
Description	Affinity Purified tyrosyl-DNA phosphodiesterase 2 Antibody
Verified Applications	ELISA, WB
Host	Rabbit
Species Cross Reactivity	Human, Mouse, Rat
Immunogen	Synthetic peptide taken within amino acid region 330-360 on human Tyrosyl-DNA phosphodiesterase protein.
Accession #	NCBI: NP_057698.2
Physical Properties
Quantity	100 µg
Volume	200 µl
Concentration	0.58 µg/µl in antibody stabilization buffer
Form	Affinity Purified
Clonality	Polyclonal
Storage	-20⁰C for long term storage
Application Protocol
DB	1:10,000
ELISA	1:10,000
Immunohistochemistry	1:50-1:150
Immunoprecipitation	1:200
Western Blot	1:1,000
Protein
Uniprot #	O95551
Overview	DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 5'-phosphodiester bond, giving rise to DNA with a free 5' phosphate. Catalyzes the hydrolysis of dead-end complexes between DNA and the topoisomerase 2 (TOP2) active site tyrosine residue.
Molecular Function	5'-tyrosyl-DNA phosphodieseterase activity, magnesium ion binding, manganese ion binding, nuclease activity, transcription corepressor activity, single-stranded DNA binding
Subcellular Location	nucleus, PML body, cytoplasm
Expression	Widely expressed
Alternative Nomenclature	5'-tyrosyl-DNA phosphodiesterase antibody AD 022 antibody dJ30M3.3 antibody EAP 2 antibody ETS 1 associated protein 2 antibody RP1-30M3.3 antibody TRAF and TNF receptor associated protein antibody TTRAP antibody Tyr DNA phosphodiesterase 2 antibody

Protein information supplied by UniProt