ITK Antibody

Product no.: ITK-101AP

$285.00

Description

General Information
Product	ITK Antibody
Verified Applications	ELISA, IHC, IP, WB
Host	Rabbit
Species Cross Reactivity	Human, Mouse, Rat
Immunogen	Synthetic peptide taken within amino acid region 550-600 on human ITK protein.
Accession #	GenBank: BAA02873.1
Physical Properties
Quantity	100 µg
Volume	200 µl
Concentration	0.54-0.57 µg/µl in antibody stabilization buffer
Form	Affinity Purified
Clonality	Polyclonal
Storage	-20⁰C for long term storage
Application Protocol
DB	1:10,000
ELISA	1:10,000
Immunohistochemistry	1:50-1:150
Immunoprecipitation	1:200
Western Blot	1:500
Protein
Uniprot #	Q08881
Overview	Tyrosine kinase that plays an essential role in regulation of the adaptive immune response. Regulates the development, function and differentiation of conventional T-cells and nonconventional NKT-cells.
Molecular Function	ATP binding, metal ion binding, non-membrane spanning protein tyrosine kinase activity
Subcellular Location	Cytoplasm (Note: Localizes in vicinity of cell surface receptors in plasma membrane after receptor stimulation)
Expression	T-cell lines and natural killer cell lines.
Alternative Nomenclature	EMT antibody Homolog of mouse T cell itk/tsk antibody IL 2 inducible T cell kinase antibody Itk antibody Kinase EMT antibody LPFS1 antibody LYK antibody MGC126257 antibody MGC126258 antibody PSCTK 2 antibody T cell specific kinase antibody TSK antibody Tyrosine protein kinase antibody Tyrosine protein kinase ITK/TSK antibody

Protein information supplied by UniProt