Lck Blocking Peptide

Product no.: P-LCK
$145.00


General Information

 

 

Product

 

Lck Peptide

Description

Antigenic Blocking Peptide Lymphocyte cell-specific protein-tyrosine kinase 

Verified Applications

Immunodepletion, Immunocompetition

Peptide Description

Synthetic peptide taken within amino acid region 500-539 on human Lymphocyte cell-specific protein-tyrosine kinase.

Accession #

GenBank: AAH13200.1


Physical Properties

 

 

Quantity

 

250 µg

Volume

100 µl

Form

Antigenic Blocking Peptide

Storage

-20C for long term storage


Application Protocol

Competition/Depletion assay

Refer to competition assay protocol


Protein

 

Uniprot #

 

P06239

Overview

Non-receptor tyrosine-protein kinase that plays an essential role in the selection and maturation of developing T-cells in the thymus and in the function of mature T-cells. Plays a key role in T-cell antigen receptor (TCR)-linked signal transduction pathways. Constitutively associated with the cytoplasmic portions of the CD4 and CD8 surface receptors. Association of the TCR with a peptide antigen-bound MHC complex facilitates the interaction of CD4 and CD8 with MHC class II and class I molecules, respectively, thereby recruiting the associated LCK protein to the vicinity of the TCR/CD3 complex.

Molecular Function

Kinase, Transferase, Tyrosine-protein kinase

Subcellular Location

Cell membrane, Cytoplasm, Membrane

Expression

Expressed specifically in lymphoid cells.

Structure

Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily.

Contains 1 protein kinase domain.

Contains 1 SH2 domain.

Contains 1 SH3 domain.

Alternative Nomenclature

IMD22 antibody

LCK antibody

Lck p56 antibody

LCK proto-oncogene, Src family tyrosine kinase antibody

Leukocyte C-terminal Src kinase antibody

LSK antibody

Lymphocyte cell specific protein tyrosine kinase antibody

Membrane associated protein tyrosine kinase antibody

Oncogene lck antibody

p56(LSTRA) protein tyrosine kinase antibody

p56-LCK antibody

pp58 lck antibody

Protein YT16 antibody

Protooncogene tyrosine protein kinase LCK antibody

T lymphocyte specific protein tyrosine kinase p56lck antibody

Tyrosine-protein kinase Lck antibody

YT 16 antibody

   

Protein information supplied by UniProt
 

 

Accessories

Product Note Status Price
Lck Antibody Lck Antibody
LCK-101AP $265.00 *
Lck Antibody BIOTIN Lck Antibody BIOTIN
LCK-BIOTIN $350.00 *
Lck Antibody FITC Lck Antibody FITC
LCK-FITC $350.00 *
Lck Positive Control Lck Positive Control
PC-LCK $185.00 *
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