Sodium / Hydrogen Exchanger 3 Antibody Positve Control

General Information

Product

Sodium / Hydrogen Exchanger 3 Antibody Western Blot Positive Control

Description

Western Blot Positive Control Sodium/Hydrogen Exchanger 3 isoform 1 Antibody

Verified Applications

WB

Immunogen

Purified Protein

Accession #

NCBI:  NP_004165.2

Physical Properties

Quantity

5 Applications

Volume

Inquire

Form

Western Blot Positive Control

Storage

-20⁰C for long term storage

Application Protocol

Western Blot

1:500

Protein

Uniprot #

P48764

Overview

Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction.

Molecular Function

PDZ domain binding; Sodium:proton antiporter activity

Subcellular Location

Apical cell membrane; Multi-pass membrane protein

Structure

Binds SLC9A3R1 and SLC9A3R2. Interacts with CHP1, CHP2 and SHANK2. Interacts with PDZK1 (via C-terminal PDZ domain) (By similarity). Interacts with PDZD3 and interactions decrease in response to elevated calcium ion levels.

Alternative Nomenclature

MGC126718 antibody

MGC126720 antibody

NHE3 antibody

SLC9A 3 antibody

Sodium/hydrogen exchanger 3 antibody

Solute carrier family 9 member 3 antibody