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General Information
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Product
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Sodium / Hydrogen Exchanger 3 Antibody Antigenic Blocking Peptide
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Description
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Antigenic Blocking Peptide Sodium/Hydrogen Exchanger 3 isoform 1
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Verified Applications
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Immunocompetition, Immunodepletion
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Peptide Description
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Synthetic Peptide
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Accession #
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NCBI: NP_004165.2
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Physical Properties
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Quantity
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250 µg
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Volume
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100 µl
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Form
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Antigenic Blocking Peptide
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Storage
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-20⁰C for long term storage
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Application Protocol
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Competition/Depletion assay
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Refer to competition assay protocol
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Protein
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Uniprot #
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P48764
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Overview
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Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction.
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Molecular Function
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PDZ domain binding; Sodium:proton antiporter activity
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Subcellular Location
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Apical cell membrane; Multi-pass membrane protein
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Structure
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Binds SLC9A3R1 and SLC9A3R2. Interacts with CHP1, CHP2 and SHANK2. Interacts with PDZK1 (via C-terminal PDZ domain) (By similarity). Interacts with PDZD3 and interactions decrease in response to elevated calcium ion levels.
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Alternative Nomenclature
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MGC126718 antibody
MGC126720 antibody
NHE3 antibody
SLC9A 3 antibody
Sodium/hydrogen exchanger 3 antibody
Solute carrier family 9 member 3 antibody
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Sodium/Hydrogen Exchanger 3 Antibody
Sodium / Hydrogen Exchanger 3 Antibody FITC
Sodium / Hydrogen Exchanger 3 Antibody BIOTIN
Sodium / Hydrogen Exchanger 3 Antibody Positve Control
