THAP1 Positive Control

Product no.: PC-THAP1
$200.00


General Information

 

 

Product

 

THAP1 Positive Control

Description

Western Blot Positive Control THAP domain-containing protein 1 Antibody

Verified Applications

WB

Immunogen

Purified protein.

Accession #

GenBank: CAG33537


Physical Properties

 

Quantity

 

5 Applications

Volume

Inquire

Form

Western Blot Positive Control

Storage

-20C for long term storage


Application Protocol

Western Blot

1:500


Protein

 

Uniprot #

 

Q9NVV9

Overview

DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression. Specifically binds the 5'-[AT]NTNN[GT]GGCA[AGT]-3' core DNA sequence and acts by modulating expression of pRB-E2F cell-cycle target genes, including RRM1. Component of a THAP1/THAP3-HCFC1-OGT complex that is required for the regulation of the transcriptional activity of RRM1. May also have pro-apoptopic activity by potentiating both serum-withdrawal and TNF-induced apoptosis.

Molecular Function

Identical protein binding, Sequence-specific DNA binding, Zinc ion binding

Subcellular Location

Nucleus > nucleoplasm, PML body

Expression

Highly expressed in heart, skeletal muscle, kidney and liver. Weaker expression in brain and placenta.

Structure

Belongs to the THAP1 family.

Alternative Nomenclature

Nuclear proapoptotic factor antibody

THAP 1 antibody

THAP domain containing apoptosis associated protein 1 antibody

THAP domain containing protein 1 antibody

THAP domain protein 1 antibody

Protein information supplied by UniProt.


Accessories

Product Note Status Price
THAP1 Antibody THAP1 Antibody
THAP1-101AP $285.00 *
THAP1 Antibody BIOTIN THAP1 Antibody BIOTIN
THAP1-BIOTIN $375.00 *
THAP1 Antibody FITC THAP1 Antibody FITC
THAP1-FITC $375.00 *
THAP1 Blocking Peptide THAP1 Blocking Peptide
P-THAP1 $155.00 *
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