PD4-401AP Publications

 

FabGennix PDE4D Antibody has been used in 38 Publications

 

Applications: Confocal microscopy, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, and Western blot

 

Reactivity: Bovine, Human, Mouse, and Rat

 

Massimi, Mara, et al. "Increase of Intracellular Cyclic AMP by PDE4 Inhibitors Affects HepG2 Cell Cycle Progression and Survival." Journal of Cellular Biochemistry (2016).

 

PMID: 27859531

Applications: Western Blot

Reactivity: Human

Petersen, T. S., et al. "Distribution and function of 3', 5'-Cyclic-AMP phosphodiesterases in the human ovary." Molecular and cellular endocrinology (2015).

 

PMID: 25578602

Applications: Immunohistochemistry

Reactivity: Human

Guo, Jiejie, et al. "Etazolate abrogates the lipopolysaccharide (LPS)-induced downregulation of the cAMP/pCREB/BDNF signaling, neuroinflammatory response and depressive-like behavior in mice." Neuroscience 263 (2014).

 

PMID: 24434771

Applications: Western Blot

Reactivity: Mouse

Dong, Cun-Jian, et al. "Presynaptic Inhibition by α2 Receptor/Adenylate Cyclase/PDE4 Complex at Retinal Rod Bipolar Synapse." The Journal of Neuroscience 34.28 (2014).

 

PMID: 25009274

Applications: Immunohistochemistry

Reactivity: Rat

Zhai, Kui, et al. "Phosphodiesterase types 3 and 4 regulate the phasic contraction of neonatal rat bladder smooth myocytes via distinct mechanisms." Cellular signalling 26.5 (2014).

 

PMID: 24463006

Applications: Western Blot

Reactivity: Rat

Salazar, Norma C et al. “GRK2 Blockade with βARKct Is Essential for Cardiac Β2-Adrenergic Receptor Signaling Towards Increased Contractility.” Cell Communication and Signaling : CCS 11 (2013).

 

PMCID: 3846709

Applications: Immunoprecipitation, Western Blot

Reactivity: Mouse

Al-Tawashi, Azza, and Chris Gehring. “Phosphodiesterase Activity Is Regulated by CC2D1A That Is Implicated in Non-Syndromic Intellectual Disability.” Cell Communication and Signaling?: CCS 11 (2013).

 

PMCID: 3704924

Applications: Immunocytochemistry, Western Blot

Reactivity: Mouse

Wang, Zhen-Zhen et al. “RNA Interference-Mediated Phosphodiesterase 4D Splice Variants Knock-down in the Prefrontal Cortex Produces Antidepressant-Like and Cognition-Enhancing Effects.” British Journal of Pharmacology 168.4 (2013).

 

PMCID: 3631387

Applications: Western Blot

Reactivity: Mouse

Michalski, Joel, et al. "Attenuation of inhibitory prostaglandin E2 signaling in Human lung fibroblasts is mediated by phosphodiesterase 4." American journal of respiratory cell and molecular biology 47.6 (2012).

 

PMID: 23043089

Applications: Western Blot

Reactivity: Human

Al-Tawashi, Azza et al. “Protein Implicated in Nonsyndromic Mental Retardation Regulates Protein Kinase A (PKA) Activity.” The Journal of Biological Chemistry 287.18 (2012).

PMCID: 3340277

Applications: Immunohistochemistry, Western Blot

Reactivity: Mouse

Keravis, Thérèse et al. “Disease Progression in MRL/lpr Lupus-Prone Mice Is Reduced by NCS 613, a Specific Cyclic Nucleotide Phosphodiesterase Type 4 (PDE4) Inhibitor.” Ed. Pierre Bobé. PLoS ONE 7.1 (2012).

 

PMCID: 3256138

Applications: Western Blot

Reactivity: Mouse

Schaal, Sandra Marie et al. “The Therapeutic Profile of Rolipram, PDE Target and Mechanism of Action as a Neuroprotectant Following Spinal Cord Injury.” Ed. Valentin Ceña. PLoS ONE 7.9 (2012).

 

PMCID: 3446989

Applications: Immunohistochemistry, Western Blot

Reactivity: Rat

Haque, Mohammed Z., Paulo S. Caceres, and Pablo A. Ortiz. “β-Adrenergic Receptor Stimulation Increases Surface NKCC2 Expression in Rat Thick Ascending Limbs in a Process Inhibited by Phosphodiesterase 4.” American Journal of Physiology - Renal Physiology 303.9 (2012).

 

PMCID: 3518189

Applications: Western Blot

Reactivity: Human

Yougbare, Issaka, et al. "NCS 613, a potent and specific PDE4 inhibitor, displays anti-inflammatory effects on Human lung tissues." American Journal of Physiology-Lung Cellular and Molecular Physiology 301.4 (2011).

 

PMID: 21784969

Applications: Immunocytochemistry, Western Blot

Reactivity: Rat

Abusnina, Abdurazzag, et al. "Down-regulation of cyclic nucleotide phosphodiesterase PDE1A is the key event of p73 and UHRF1 deregulation in thymoquinone-induced acute lymphoblastic leukemia cell apoptosis." Cellular signalling 23.1 (2011).

 

PMID: 20807569

Applications: Western Blot

Reactivity: Human

Adderley, Shaquria P. et al. “Identification of Cytosolic Phosphodiesterases in the Erythrocyte: A Possible Role for PDE5.” Medical Science Monitor: International Medical Journal of Experimental and Clinical Research 17.5 (2011).

 

PMCID: 3366467

Applications: Western Blot

Reactivity: Human

Gregg, Christopher J., et al. "β2-adrenergic receptor-coupled phosphoinositide 3-kinase constrains cAMP-dependent increases in cardiac inotropy through phosphodiesterase 4 activation." Anesthesia & Analgesia 111.4 (2010).

 

PMID: 20705779

Applications: Western Blot

Reactivity: Mouse

Wang, Jianjie, Susan Bingaman, and Virginia H. Huxley. “Intrinsic Sex-Specific Differences in Microvascular Endothelial Cell Phosphodiesterases.” American Journal of Physiology - Heart and Circulatory Physiology 298.4 (2010).

 

PMCID: 2853420

Applications: Confocal microscopy, Immunofluorescence, Western Blot

Reactivity: Rat

Tahseldar-Roumieh, Rima et al. “PDEs1-5 Activity and Expression in Tissues of Cirrhotic Rats Reveal a Role for Aortic PDE3 in NO Desensitization.” International Journal of Experimental Pathology 90.6 (2009).

 

PMCID: 2803251

Applications: Western Blot

Reactivity: Rat

Li, Yuting et al. “Regulation of Amygdalar PKA by β-Arrestin-2/phosphodiesterase-4 Complex Is Critical for Fear Conditioning.”Proceedings of the National Academy of Sciences of the United States of America 106.51 (2009).

 

PMCID: 2799795

Applications: Immunoprecipitation, Western Blot

Reactivity: Mouse

Dostaler-Touchette, V., et al. "Cyclic adenosine monophosphate (cAMP)-specific phosphodiesterase is functional in bovine mammary gland." Journal of dairy science 92.8 (2009).

 

PMID: 21653225

Applications: Immunocytochemistry

Reactivity: Bovine

Whitaker, Christopher M., and Nigel G. F. Cooper. “The Novel Distribution of Phosphodiesterase-4 Subtypes Within the Rat Retina.” Neuroscience 163.4 (2009).

PMCID: 2774823

Applications: Confocal microscopy, Immunofluorescence, Immunohistochemistry, Western Blot

Reactivity: Rat

Nomura-Furuwatari, Chizumi, et al. "Expression profiles of phosphodiesterase 4D splicing variants in osteoblastic cells." Journal of bone and mineral metabolism 26.2 (2008).

 

PMID: 18301971

Applications: Western Blot

Reactivity: Mouse

Zhang, Han-Ting, et al. "Anxiogenic-like behavioral phenotype of mice deficient in phosphodiesterase 4B (PDE4B)." Neuropsychopharmacology 33.7 (2008).

 

PMID: 17700644

Applications: Western Blot

Reactivity: Mouse

Whitaker, Christopher M. et al. “Rolipram Attenuates Acute Oligodendrocyte Death in the Adult Rat Ventrolateral Funiculus Following a Contusive Cervical Spinal Cord Injury.” Neuroscience letters 438.2 (2008).

 

PMCID: 2530896

Applications: Confocal microscopy, Immunofluorescence

Reactivity: Rat

Lin, Rui, et al. "Changes in β 2-adrenoceptor and other signaling proteins produced by chronic administration of ‘β-blockers’ in a murine asthma model." Pulmonary pharmacology & therapeutics 21.1 (2008).

 

PMCID: 2775056

Applications: Western Blot

Reactivity: Mouse

Creighton, Judy, et al. "Spectrin-anchored phosphodiesterase 4D4 restricts cAMP from disrupting microtubules and inducing endothelial cell gap formation." Journal of cell science 121.1 (2008).

 

PMID: 18073242

Applications: Immunoprecipitation, Western Blot

Reactivity: Human

Fujita, Masahiro, et al. "In vivo and in vitro measurement of brain phosphodiesterase 4 in Rats after antidepressant administration." Synapse 61.2 (2007).

 

PMID: 17117418

Applications: Western Blot

Reactivity: Rat

Sachs, Benjamin D. et al. “P75 Neurotrophin Receptor Regulates Tissue Fibrosis through Inhibition of Plasminogen Activation via a PDE4/cAMP/PKA Pathway.” The Journal of Cell Biology 177.6 (2007).

 

PMCID: 2064370

Applications: Coimmunoprecipitation,

Western Blot

Reactivity: Mouse

Terrin, Anna et al. “PGE1 Stimulation of HEK293 Cells Generates Multiple Contiguous Domains with Different [cAMP]: Role of Compartmentalized Phosphodiesterases.” The Journal of Cell Biology 175.3 (2006).

 

PMCID: 2064521

Applications: Confocal microscopy, Immunofluorescence

Reactivity: Human

Dlaboga, Daniel, Hassan Hajjhussein, and James M. O'Donnell. "Regulation of phosphodiesterase-4 (PDE4) expression in Mouse brain by repeated antidepressant treatment: comparison with rolipram." Brain research 1096.1 (2006).

 

PMID: 16730340

Applications: Western Blot

Reactivity: Mouse

Baxendale, Rhona W., and Lynn R. Fraser. "Mammalian sperm phosphodiesterases and their involvement in receptor‐mediated cell signaling important for capacitation." Molecular reproduction and development 71.4 (2005).

 

PMID: 15856425

Applications: Immunofluorescence, Western Blot

Reactivity: Mouse

Giorgi, Mauro, et al. "The induction of cyclic nucleotide phosphodiesterase 4 gene (PDE4D) impairs memory in a water maze task." Behavioural brain research 154.1 (2004).

 

PMID: 15302115

Applications: Western Blot

Reactivity: Rat

Gallagher, Helen C., et al. "Valproate activates phosphodiesterase-mediated cAMP degradation: relevance to C6 glioma G1 phase progression." Neurotoxicology and teRatology 26.1 (2004).

 

PMID: 15001216

Applications: Western Blot

Reactivity: Human

Wang, Daguang, et al. "Cloning and characterization of novel PDE4D isoforms PDE4D6 and PDE4D7." Cellular signalling 15.9 (2003).

 

PMID: 12834813

Applications: Western Blot

Reactivity: Human

Valente, Eliane GA, et al. "L-arginine and phosphodiesterase (PDE) inhibitors counteract fibrosis in the Peyronie’s fibrotic plaque and related fibroblast cultures." Nitric Oxide 9.4 (2003).

 

PMCID: 14996430

Applications: Immunohistochemistry, Western Blot

Reactivity: Human, Rat

Kapiloff, Michael S., Nicole Jackson, and Nathan Airhart. "mAKAP and the ryanodine receptor are part of a multi-component signaling complex on the cardiomyocyte nuclear envelope." Journal of Cell Science 114.17 (2001).

 

PMID: 11590243

Applications: Immunohistochemistry, Immunoprecipitation, Western Blot

Reactivity: Human, Rat

Farooqui, Shakeel M., et al. "Surgically induced cryptorchidism-related degenerative changes in spermatogonia are associated with loss of cyclic adenosine monophosphate-dependent phosphodiesterases type 4 in abdominal testes of rats." Biology of reproduction 64.6 (2001).

 

PMCID: 11369582

Applications: Confocal microscopy, Immunocytochemistry, Western Blot

Reactivity: Rat

   

 

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