PD4A-112AP Publications

 

FabGennix PDE4A Antibody has been used in 47 Publications

 

Applications: Confocal microscopy, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunocytochemistry, Immunohistochemistry, and Western blot

 

Reactivity: Human, Moose, Mouse, and Rat

 

Avila, Diana V., et al. "Dysregulation of hepatic cAMP levels via altered Pde4b expression plays a critical role in alcohol‐induced steatosis." The Journal of pathology 240.1 (2016).

 

PMID: 27287961

Applications: Western Blot

Reactivity: Rat

Massimi, Mara, et al. "Increase of Intracellular Cyclic AMP by PDE4 Inhibitors Affects HepG2 Cell Cycle Progression and Survival." Journal of Cellular Biochemistry (2016).

 

PMID: 27859531

Applications: Western Blot

Reactivity: Human

Kedia, George T., et al. "Expression and Distribution of Phosphodiesterase Isoenzymes in the Human Male Urethra." Urology (2015).

PMID: 25704994

Applications: Immunohistochemistry, Western Blot

Reactivity: Human

Petersen, T. S., et al. "Distribution and function of 3', 5'-Cyclic-AMP phosphodiesterases in the human ovary." Molecular and cellular endocrinology (2015).

 

PMID: 25578602

Applications: Immunohistochemistry

Reactivity: Human

Guo, Jiejie, et al. "Etazolate abrogates the lipopolysaccharide (LPS)-induced downregulation of the cAMP/pCREB/BDNF signaling, neuroinflammatory response and depressive-like behavior in mice." Neuroscience 263 (2014).

 

PMID: 24434771

Applications: Western Blot

Reactivity: Mouse

Zhai, Kui, et al. "Phosphodiesterase types 3 and 4 regulate the phasic contraction of neonatal rat bladder smooth myocytes via distinct mechanisms." Cellular signalling 26.5 (2014).

 

PMID: 23347325

Applications: Western Blot

Reactivity: Rat

Amanda, G. Vang, et al. "Regulatory T-cells and cAMP suppress effector T-cells independently of PKA-CREM/ICER: a potential role for Epac." Biochemical Journal 456.3 (2013).

 

PMCID: 24007532

Applications: Western Blot

Reactivity: Mouse

Wang, Zhen-Zhen et al. “RNA Interference-Mediated Phosphodiesterase 4D Splice Variants Knock-down in the Prefrontal Cortex Produces Antidepressant-Like and Cognition-Enhancing Effects.” British Journal of Pharmacology 168.4 (2013).

 

PMCID: 3631387

Applications: Western Blot

Reactivity: Mouse

Yougbaré, Issaka, et al. "NCS 613 Exhibits Anti-Inflammatory Effects On Pbmcs From Lupus Patients By Inhibiting P38 MAPK And NF-Κb Signalling Pathways While Reducing Proinflammatory Cytokine Production." Canadian Journal Of Physiology & Pharmacology 91.5 (2013).

 

PMCID: 23656347

Applications: Immunocytochemistry, Western Blot

Reactivity: Human

Schaal, Sandra Marie et al. “The Therapeutic Profile of Rolipram, PDE Target and Mechanism of Action as a Neuroprotectant Following Spinal Cord Injury.” Ed. Valentin Ceña. PLoS ONE 7.9 (2012).

PMID: 3446989

Applications: Confocal microscopy, Immunofluorescence, Immunohistochemistry, Western Blot

Reactivity: Rat

Haque, Mohammed Z., Paulo S. Caceres, and Pablo A. Ortiz. “β-Adrenergic Receptor Stimulation Increases Surface NKCC2 Expression in Rat Thick Ascending Limbs in a Process Inhibited by Phosphodiesterase 4.” American Journal of Physiology - Renal Physiology 303.9 (2012).

 

PMCID: 3518189

Applications: Western Blot

Reactivity: Rat

Yougbare, Issaka, et al. "NCS 613, a potent and specific PDE4 inhibitor, displays anti-inflammatory effects on Human lung tissues." American Journal of Physiology-Lung Cellular and Molecular Physiology 301.4 (2011).

 

PMCID: 21784969

Applications: Immunocytochemistry, Western Blot

Reactivity: Human

Abusnina, Abdurazzag, et al. "Down-regulation of cyclic nucleotide phosphodiesterase PDE1A is the key event of p73 and UHRF1 deregulation in thymoquinone-induced acute lymphoblastic leukemia cell apoptosis." Cellular signalling 23.1 (2011).

 

PMID: 20807569

Applications: Western Blot

Reactivity: Human

Ückert, Stefan, et al. "Expression and distribution of phosphodiesterase isoenzymes in the Human seminal vesicles." The journal of sexual medicine 8.11 (2011).

PMID: 21810184

Applications: Immunohistochemistry, Western Blot

Reactivity: Human

Li, Yun-Feng et al. “Phosphodiesterase-4D Knockout and RNAi-Mediated Knockdown Enhance Memory and Increase Hippocampal Neurogenesis via Increased cAMP Signaling.” The Journal of neuroscience : the official journal of the Society for Neuroscience 31.1 (2011).

 

PMCID: 3079568

Applications: Western Blot

Reactivity: Mouse

Richter, Wito et al. “Conserved Expression and Functions of PDE4 in Rodent and Human Heart.” Basic Research in Cardiology 106.2 (2011).

PMCID: 3032896

Applications: Immunoprecipitation, Western Blot

Reactivity: Human, Mouse, Rat

Fatemi, S. Hossein, et al. "Levels of phosphodiesterase 4A and 4B are altered by chronic treatment with psychotropic medications in Rat frontal cortex." Synapse 64.7 (2010).

 

PMID: 20222156

Applications: Western Blot

Reactivity: Rat

Waldkirch, Eginhard, et al. "Expression of cAMP-dependent protein kinase isoforms in the Human prostate: functional significance and relation to PDE4." Urology 76.2 (2010).

 

PMID: 20599254

Applications: Western Blot

Reactivity: Human

Waldkirch, Eginhard S., et al. "Expression of Cyclic AMP‐dependent Protein Kinase Isoforms in Human Cavernous Arteries: Functional Significance and Relation to Phosphodiesterase Type 4." The journal of sexual medicine 7.6 (2010).

 

PMID: 20487244

Applications: Immunohistochemistry, Western Blot

Reactivity: Human

Vedin, Viktoria, Björn Eriksson, and Anna Berghard. "Organization of the chemosensory neuroepithelium of the vomeronasal organ of the Scandinavian moose Alces alces." Brain research 1306 (2010).

 

PMCID: 19833105

Applications: Immunohistochemistry

Reactivity: Moose

Whitaker, Christopher M., and Nigel G. F. Cooper. “The Novel Distribution of Phosphodiesterase-4 Subtypes Within the Rat Retina.” Neuroscience 163.4 (2009).

PMCID: 2774823

Applications: Immunohistochemistry, Western Blot

Reactivity: Rat

Liu, Cambrian Y., Scott E. Fraser, and David S. Koos. "Grueneberg ganglion olfactory subsystem employs a cGMP signaling pathway." Journal of CompaRative Neurology 516.1 (2009).

 

PMID: 19565523

Applications: Immunofluorescence, Western Blot

Reactivity: Rat

Hörnberg, Maria, et al. "Retinoic Acid Selectively Inhibits Death Of Basal Vomeronasal Neurons During Late Stage Of Neural Circuit Formation." Journal Of Neurochemistry 110.4 (2009).

 

PMID: 19519663

Applications: Confocal microscopy, Immunohistochemistry

Reactivity: Mouse

Tahseldar-Roumieh, Rima et al. “PDEs1-5 Activity and Expression in Tissues of Cirrhotic Rats Reveal a Role for Aortic PDE3 in NO Desensitization.” International Journal of Experimental Pathology 90.6 (2009).

 

PMCID: 2803251

Applications: Western Blot

Reactivity: Rat

Goldhoff, Patricia et al. “CCR-08-0827 Version 2 Targeted Inhibition of Cyclic AMP Phosphodiesterase-4 Promotes Brain Tumor Regression.” Clinical cancer research : an official journal of the American Association for Cancer Research 14.23 (2008).

 

PMCID: 2615415

Applications: Immunohistochemistry, Western Blot

Reactivity: Mouse

Dlaboga, Daniel, Hassan Hajjhussein, and James M. O'Donnell. "Chronic haloperidol and clozapine produce different patterns of effects on phosphodiesterase-1B,-4B, and-10A expression in Rat striatum." Neuropharmacology 54.4 (2008).

 

PMID: 18222493

Applications: Western Blot

Reactivity: Rat

Whitaker, Christopher M. et al. “Rolipram Attenuates Acute Oligodendrocyte Death in the Adult Rat Ventrolateral Funiculus Following a Contusive Cervical Spinal Cord Injury.” Neuroscience letters 438.2 (2008).

 

PMCID: 2530896

Applications: Confocal Microscopy, Immunofluorescence

Reactivity: Rat

Zhang, Han-Ting, et al. "Anxiogenic-like behavioral phenotype of mice deficient in phosphodiesterase 4B (PDE4B)." Neuropsychopharmacology 33.7 (2008).

 

PMID: 17700644

Applications: Western Blot

Reactivity: Mouse

Fatemi, S. Hossein, et al. "Phosphodiesterase-4A expression is reduced in cerebella of patients with bipolar disorder." Psychiatric genetics 18.6 (2008).

 

PMID: 19018233

Applications: Western Blot

Reactivity: Human

Albrecht, Knut, et al. "Immunohistochemical distribution of cyclic nucleotide phosphodiesterase (PDE) isoenzymes in the Human vagina: A potential forensic value?." Journal of forensic and legal medicine 14.5 (2007).

 

PMID: 17113813

Applications: Immunohistochemistry

Reactivity: Human

Braun, Natalie N., et al. "Expression of phosphodiesterase 4 is altered in the brains of subjects with autism." Neuroreport 18.17 (2007).

 

PMID: 18090323

Applications: Western Blot

Reactivity: Human

Bora, Roop Singh, et al. "A reporter gene assay for screening of PDE4 subtype selective inhibitors." Biochemical and biophysical research communications 356.1 (2007).

PMID: 17336928

Applications: Immunocytochemistry, Western Blot

Reactivity: Mouse

Sachs, Benjamin D. et al. “P75 Neurotrophin Receptor Regulates Tissue Fibrosis through Inhibition of Plasminogen Activation via a PDE4/cAMP/PKA Pathway.” The Journal of Cell Biology 177.6 (2007).

 

PMCID: 2064370

Applications: Immunoprecipitation, Western Blot

Reactivity: Mouse

Fujita, Masahiro, et al. "In vivo and in vitro measurement of brain phosphodiesterase 4 in Rats after antidepressant administration." Synapse 61.2 (2007).

 

PMID: 17117418

Applications: Western Blot

Reactivity: Rat

Peter, Daniel, et al. "Differential expression and function of phosphodiesterase 4 (PDE4) subtypes in human primary CD4+ T cells: predominant role of PDE4D." The Journal of Immunology 178.8 (2007).

 

PMID: 17404263

Applications: Immunoprecipitation, Western Blot

Reactivity: Human

Vernet, Dolores, et al. "Phosphodiesterase type 5 is not upregulated by tadalafil in cultures of Human penile cells." The journal of sexual medicine 3.1 (2006).

 

PMID: 16409221

Applications: Immunocytochemistry

Reactivity: Human

Oelke, Matthias, et al. "Expression of cAMP and cGMP-phosphodiesterase isoenzymes 3, 4, and 5 in the Human clitoris: immunohistochemical and molecular biology study." Urology 67.5 (2006).

 

PMID: 16635522

Applications: Confocal microscopy, Immunofluorescence

Reactivity: Human

Dlaboga, Daniel, Hassan Hajjhussein, and James M. O'Donnell. "Regulation of phosphodiesterase-4 (PDE4) expression in Mouse brain by repeated antidepressant treatment: comparison with rolipram." Brain research 1096.1 (2006).

 

PMID: 16730340

Applications: Western blot

Reactivity: Human

Ückert, Stefan, et al. "Cyclic adenosine monophosphate and cyclic guanosine monophosphate-phosphodiesterase isoenzymes in Human vagina: relation to nitric oxide synthase isoforms and vasoactive intestinal polypeptide-containing nerves." Urology 65.3 (2005).

 

PMID: 15780401

Applications: Immunohistochemistry

Reactivity: Human

Baxendale, Rhona W., and Lynn R. Fraser. "Mammalian sperm phosphodiesterases and their involvement in Receptor mediated cell signaling important for capacitation." Molecular reproduction and development 71.4 (2005).

 

PMID: 15856425

Applications: Immunofluorescence, Western Blot

Reactivity: Human

Weyrich, Andrew S., et al. "Dipyridamole selectively inhibits inflammatory gene expression in platelet–monocyte aggregates." Circulation 111.5 (2005).

 

PMID: 15668340

Applications: Western blot

Reactivity: Human

Asirvatham, Angela L., et al. "A-kinase anchoring proteins interact with phosphodiesterases in T lymphocyte cell lines." The Journal of Immunology 173.8 (2004).

PMCID: 15470020

Applications: Confocal microscopy, Immunofluorescence, Immunoprecipitation

Reactivity: Human

Gallagher, Helen C., et al. "Valproate activates phosphodiesterase-mediated cAMP degradation: relevance to C6 glioma G1 phase progression." Neurotoxicology and Teratology 26.1 (2004).

 

PMID: 15001216

Applications: Western blot

Reactivity: Human

Norlin, E. Marianne, Fredrik Gussing, and Anna Berghard. "Vomeronasal phenotype and behavioral alterations in Gαi2 mutant mice." Current biology 13.14 (2003).

 

PMID: 12867032

Applications: Immunohistochemistry

Reactivity: Mouse

Valente, Eliane GA, et al. "L-arginine and phosphodiesterase (PDE) inhibitors counteract fibrosis in the Peyronie’s fibrotic plaque and related fibroblast cultures." Nitric Oxide 9.4 (2003).

 

PMID: 14996430

Applications: Immunohistochemistry, Western Blot

Reactivity: Human

Ückert, Stefan, et al. "Interactions between cGMP-and cAMP-pathways are involved in the regulation of penile smooth muscle tone." World journal of urology 22.4 (2004).

 

PMID: 15045518

Applications: Immunohistochemistry

Reactivity: Human

Farooqui, Shakeel M., et al. "Surgically induced cryptorchidism-related degenerative changes in spermatogonia are associated with loss of cyclic adenosine monophosphate-dependent phosphodiesterases type 4 in abdominal testes of rats." Biology of reproduction 64.6 (2001).

 

PMID: 11369582

Applications: Confocal microscopy, Immunocytochemistry, Western blot

Reactivity: Rat

   

 

Publishing research using PD4A-112AP? Please let us know, we can cite the reference in this datasheet.