PD4B-201AP Publications

 

FabGennix PDE4B Antibody has been used in 43 Publications

 

Applications: Coimmunoprecipitation, Confocal microscopy, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation and Western blot

 

Reactivity: Human, Mouse, and Pig, Rat

 

Massimi, Mara, et al. "Increase of Intracellular Cyclic AMP by PDE4 Inhibitors Affects HepG2 Cell Cycle Progression and Survival." Journal of Cellular Biochemistry (2016).

 

PMID: 27859531

Applications: Western Blot

Reactivity: Human

Kedia, George T., et al. "Expression and Distribution of Phosphodiesterase Isoenzymes in the Human Male Urethra." Urology (2015).

PMID: 25704994

Applications: Immunofluorescence, Western Blot

Reactivity: Human

Petersen, T. S., et al. "Distribution and function of 3', 5'-Cyclic-AMP phosphodiesterases in the human ovary." Molecular and cellular endocrinology (2015).

 

PMID: 25578602

Applications: Immunohistochemistry

Reactivity: Human

Guo, Jiejie, et al. "Etazolate abrogates the lipopolysaccharide (LPS)-induced downregulation of the cAMP/pCREB/BDNF signaling, neuroinflammatory response and depressive-like behavior in mice." Neuroscience 263 (2014).

 

PMID: 24434771

Applications: Western Blot

Reactivity: Mouse

Zhai, Kui, et al. "Phosphodiesterase types 3 and 4 regulate the phasic contraction of neonatal rat bladder smooth myocytes via distinct mechanisms." Cellular signalling 26.5 (2014).

 

PMCID: 24463006

Applications: Western Blot

Reactivity: Human

Hiramoto, Kenichi, et al. "Role of phosphodiesterase 2 in growth and invasion of human malignant melanoma cells." Cellular signalling 26.9 (2014).

 

PMID: 24705027

Applications: Western Blot

Reactivity: Rat

Wang, Zhen-Zhen et al. “RNA Interference-Mediated Phosphodiesterase 4D Splice Variants Knock-down in the Prefrontal Cortex Produces Antidepressant-Like and Cognition-Enhancing Effects.” British Journal of Pharmacology 168.4 (2013).

 

PMID: 23003922

Applications: Western Blot

Reactivity: Mouse

Sanabra, Cristina, Emily M. Johansson, and Guadalupe Mengod. "Critical role for PDE4 subfamilies in the development of experimental autoimmune encephalomyelitis." Journal of chemical neuroanatomy 47 (2013).

 

PMID: 23274837

Applications: Immunohistochemistry

Reactivity: Mouse

Yougbaré, Issaka, et al. "NCS 613 Exhibits Anti-Inflammatory Effects On Pbmcs From Lupus Patients By Inhibiting P38 MAPK And NF-Κb Signalling Pathways While Reducing Proinflammatory Cytokine Production." Canadian Journal Of Physiology & Pharmacology 91.5 (2013).

 

PMID: 23656347

Applications: Immunocytochemistry, Western Blot

Reactivity: Human

Haque, Mohammed Z., Paulo S. Caceres, and Pablo A. Ortiz. “β-Adrenergic Receptor Stimulation Increases Surface NKCC2 Expression in Rat Thick Ascending Limbs in a Process Inhibited by Phosphodiesterase 4.” American Journal of Physiology - Renal Physiology 303.9 (2012).

 

PMCID: 3518189

Applications: Western Blot

Reactivity: Rat

Johansson, Emily M., Cristina Sanabra, and Guadalupe Mengod. "Sex‐related differences of cAMP‐specific PDE4B3 mRNA in oligodendrocytes following systemic inflammation." Glia 60.12 (2012).

 

PMID: 22848007

Applications: Western Blot

Reactivity: Mouse

Schaal, Sandra Marie et al. “The Therapeutic Profile of Rolipram, PDE Target and Mechanism of Action as a Neuroprotectant Following Spinal Cord Injury.” Ed. Valentin Ceña. PLoS ONE 7.9 (2012).

 

PMID: 3446989

Applications: Immunohistochemistry, Western Blot

Reactivity: Rat

Richter, Wito et al. “Conserved Expression and Functions of PDE4 in Rodent and Human Heart.” Basic Research in Cardiology 106.2 (2011).

PMCID: 3032896

Applications: Immunoprecipitation, Western Blot

Reactivity: Human, Mouse, Rat

Yougbare, Issaka, et al. "NCS 613, a potent and specific PDE4 inhibitor, displays anti-inflammatory effects on Human lung tissues." American Journal of Physiology-Lung Cellular and Molecular Physiology 301.4 (2011).

 

PMID: 21784969

Applications: Immunocytochemistry, Western Blot

Reactivity: Human

Ückert, Stefan, et al. "Expression and distribution of phosphodiesterase isoenzymes in the Human seminal vesicles." The journal of sexual medicine 8.11 (2011).

PMID: 21810184

Applications: Immunocytochemistry, Western Blot

Reactivity: Human, Pig

Li, Yun-Feng et al. “Phosphodiesterase-4D Knockout and RNAi-Mediated Knockdown Enhance Memory and Increase Hippocampal Neurogenesis via Increased cAMP Signaling.” The Journal of neuroscience : the official journal of the Society for Neuroscience 31.1 (2011).

 

PMCID: 3079568

Applications: Immunohistochemistry, Western Blot

Reactivity: Mouse

Abusnina, Abdurazzag, et al. "Down-regulation of cyclic nucleotide phosphodiesterase PDE1A is the key event of p73 and UHRF1 deregulation in thymoquinone-induced acute lymphoblastic leukemia cell apoptosis." Cellular signalling 23.1 (2011).

 

PMID: 20807569

Applications: Western Blot

Reactivity: Human

Waldkirch, Eginhard S., et al. "Expression of Cyclic AMP‐dependent Protein Kinase Isoforms in Human Cavernous Arteries: Functional Significance and Relation to Phosphodiesterase Type 4." The journal of sexual medicine 7.6 (2010).

 

PMID: 20487244

Applications: Immunohistochemistry, Western Blot

Reactivity: Human

Waldkirch, Eginhard, et al. "Expression of cAMP-dependent protein kinase isoforms in the Human prostate: functional significance and relation to PDE4." Urology 76.2 (2010).

 

PMCID: 20599254

Applications: Western Blot

Reactivity: Human

Fatemi, S. Hossein, et al. "Levels of phosphodiesterase 4A and 4B are altered by chronic treatment with psychotropic medications in Rat frontal cortex." Synapse 64.7 (2010).

 

PMCID: 20222156

Applications: Western Blot

Reactivity: Rat

Nikolova, Sevdalina et al. “Phosphodiesterase 6 Subunits Are Expressed and Altered in Idiopathic Pulmonary Fibrosis.” Respiratory Research 11.1 (2010).

 

PMCID: 2988012

Applications: Western Blot

Reactivity: Human, Pig

Whitaker, Christopher M., and Nigel G. F. Cooper. “The Novel Distribution of Phosphodiesterase-4 Subtypes Within the Rat Retina.” Neuroscience 163.4 (2009).

 

PMCID: 2774823

Applications: Confocal microscopy, Immunofluorescence, Western Blot

Reactivity: Rat

Fatemi, S. Hossein, et al. "PDE4B polymorphisms and decreased PDE4B expression are associated with schizophrenia." Schizophrenia research 101.1 (2008).

 

PMID: 18394866

Applications: Western Blot

Reactivity: Human

Dlaboga, Daniel, Hassan Hajjhussein, and James M. O'Donnell. "Chronic haloperidol and clozapine produce different patterns of effects on phosphodiesterase-1B,-4B, and-10A expression in Rat striatum." Neuropharmacology 54.4 (2008).

 

PMID: 18222493

Applications: Western Blot

Reactivity: Rat

Zhang, Han-Ting, et al. "Anxiogenic-like behavioral phenotype of mice deficient in phosphodiesterase 4B (PDE4B)." Neuropsychopharmacology 33.7 (2008).

 

PMID: 17700644

Applications: Western Blot

Reactivity: Mouse

Zhang, Lingzhi et al. “Cyclic Nucleotide Phosphodiesterase Profiling Reveals Increased Expression of Phosphodiesterase 7B in Chronic Lymphocytic Leukemia.” Proceedings of the National Academy of Sciences of the United States of America 105.49 (2008).

 

PMCID: 2614795

Applications: Western Blot

Reactivity: Human

Whitaker, Christopher M. et al. “Rolipram Attenuates Acute Oligodendrocyte Death in the Adult Rat Ventrolateral Funiculus Following a Contusive Cervical Spinal Cord Injury.” Neuroscience letters 438.2 (2008).

 

PMCID: 2530896

Applications: Confocal microscopy, Immunofluorescence

Reactivity: Rat

Tawar, Urmila, et al. "Renal phosphodiesterase 4B is activated in the Dahl salt-sensitive Rat." Hypertension 51.3 (2008).

 

PMID: 18227403

Applications: Immunohistochemistry, Western Blot

Reactivity: Rat

Kim, Jong-So, et al. "Daily rhythm in pineal phosphodiesterase (PDE) activity reflects adrenergic/3′, 5′-cyclic adenosine 5′-monophosphate induction of the PDE4B2 variant." Endocrinology 148.4 (2007.

 

PMID: 17204557

Applications: Western Blot

Reactivity: Rat

Bora, Roop Singh, et al. "A reporter gene assay for screening of PDE4 subtype selective inhibitors." Biochemical and biophysical research communications 356.1 (2007).

 

PMID: 17336928

Applications: Immunocytochemistry, Western Blot

Reactivity: Rat

Sachs, Benjamin D. et al. “P75 Neurotrophin Receptor Regulates Tissue Fibrosis through Inhibition of Plasminogen Activation via a PDE4/cAMP/PKA Pathway.” The Journal of Cell Biology 177.6 (2007).

PMCID: 2064370

Applications: Coimmunoprecipitation, Western Blot

Reactivity: Rat

Fujita, Masahiro, et al. "In vivo and in vitro measurement of brain phosphodiesterase 4 in Rats after antidepressant administration." Synapse 61.2 (2007).

 

PMID: 17117418

Applications: Western Blot

Reactivity: Rat

Braun, Natalie N., et al. "Expression of phosphodiesterase 4 is altered in the brains of subjects with autism." Neuroreport 18.17 (2007).

 

PMID: 18090323

Applications: Western Blot

Reactivity: Human

Vernet, Dolores, et al. "Phosphodiesterase type 5 is not upregulated by tadalafil in cultures of Human penile cells." The journal of sexual medicine 3.1 (2006).

 

PMID: 16409221

Applications: Immunocytochemistry

Reactivity: Human

Busch, Cornelius J., et al. "Nitric oxide induces phosphodiesterase 4B expression in Rat pulmonary artery smooth muscle cells." American Journal of Physiology-Lung Cellular and Molecular Physiology 290.4 (2006).

 

PMID: 16299053

Applications: Western Blot

Reactivity: Rat

Terrin, Anna, et al. "PGE1 stimulation of HEK293 cells generates multiple contiguous domains with different [cAMP]: role of compartmentalized phosphodiesterases." The Journal of cell biology 175.3 (2006).

 

PMID: 17088426

Applications: Confocal Imaging

Reactivity: Human

Dlaboga, Daniel, Hassan Hajjhussein, and James M. O'Donnell. "Regulation of phosphodiesterase-4 (PDE4) expression in Mouse brain by repeated antidepressant treatment: comparison with rolipram." Brain research 1096.1 (2006).

 

PMID: 16730340

Applications: Western Blot

Reactivity: Mouse

Baxendale, Rhona W., and Lynn R. Fraser. "Mammalian sperm phosphodiesterases and their involvement in receptor‐mediated cell signaling important for capacitation." Molecular reproduction and development 71.4 (2005).

 

PMID: 15856425

Applications: Immunofluorescence, Western Blot

Reactivity: Human

Ückert, Stefan, et al. "Cyclic adenosine monophosphate and cyclic guanosine monophosphate-phosphodiesterase isoenzymes in Human vagina: relation to nitric oxide synthase isoforms and vasoactive intestinal polypeptide-containing nerves." Urology 65.3 (2005).

 

PMID: 15780401

Applications: Immunohistochemistry

Reactivity: Human

Gallagher, Helen C., et al. "Valproate activates phosphodiesterase-mediated cAMP degradation: relevance to C6 glioma G1 phase progression." Neurotoxicology and teRatology 26.1 (2004).

 

PMID: 15001216

Applications: Western Blot

Reactivity: Human

Giorgi, Mauro, et al. "The induction of cyclic nucleotide phosphodiesterase 4 gene (PDE4D) impairs memory in a water maze task." Behavioural brain research 154.1 (2004).

 

PMID: 15302115

Applications: Western Blot

Reactivity: Rat

Valente, Eliane GA, et al. "L-arginine and phosphodiesterase (PDE) inhibitors counteract fibrosis in the Peyronie’s fibrotic plaque and related fibroblast cultures." Nitric Oxide 9.4 (2003).

 

PMID: 14996430

Applications: Immunocytochemistry, Western Blot

Reactivity: Human, Rat

Farooqui, Shakeel M., et al. "Surgically induced cryptorchidism-related degenerative changes in spermatogonia are associated with loss of cyclic adenosine monophosphate-dependent phosphodiesterases type 4 in abdominal testes of rats." Biology of reproduction 64.6 (2001).

 

PMID: 11369582

Applications: Confocal microscopy, Immunocytochemistry, Western Blot

Reactivity: Human, Rat

   

 

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