5HT1B Antibody

Product no.: 5HT1B-201AP

General Information

 

 

Product

 

5HT1B Receptor Antibody

Description

Affinity Purified 5 Hydroxytryptamine 1B receptor Antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 160-260 on rat 5HT1B


Physical Properties

 

 

Quantity

 

100 µg

Volume

200 µl

Concentration

0.5-1.5 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20C for long term storage


Application Protocol

 

DB

1:50,000

ELISA

1:50,000

Immunoprecipitation

1:200

Western Blot

1:2,500-1:5,000


Protein

 

 

Uniprot #

 

P28334

Overview

G-protein coupled receptor for serotonin (5-hydroxytryptamine).   Functions as a receptor for various drugs which cause conformational change upon ligand binding that triggers signaling via guanine nucleo-tide binding proteins and modulation of down-stream effectors like adenylate cyclase.  Inhibits adenylate cyclase activity and activates phosphatidylinositol-calcium second messenger system that regulates release of intracellular Calcium ions.

Molecular Function

Drug binding, serotonin receptor activity, serotonin binding

Subcellular Location

Cell membrane; Multi-pass protein

Structure

Homodimer. Heterodimer with HTR1D

Alternative Nomenclature

HTR1DB antibody

S12 antibody

Serotonin 1D beta receptor antibody

Protein information supplied by UniProt

Accessories

Product Note Status Price
5HT1B Antibody FITC 5HT1B Antibody FITC
5HT1B-FITC
5HT1B Antibody BIOTIN 5HT1B Antibody BIOTIN
5HT1B-BIOTIN
5HT1B Blocking Peptide 5HT1B Blocking Peptide
P-5HT1B
5HT1B Positive Control 5HT1B Positive Control
PC-5HT1B
Display accessory details

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